The San Francisco 49ers need a rebound-win in the worst way after suffering a second-straight loss Sunday. This time being at home to the Indianapolis Colts, and they now hit the road in a divisional game against the St. Louis Rams.
They’ve already lost one of their top defensive players in Aldon Smith, and no one knows when he’ll return, so they need everyone else to play Thursday night against a Rams team that they were unable to defeat last year.
Two players they can’t afford to be without is All-Pro tight end Vernon Davis and All-Pro middle linebacker Patrick Willis, and both players are being listed as questionable for Thursday’s showdown vs the Rams.
Davis is dealing with a hamstring injury and missed the Week Three loss to the Colts, practiced Monday and Tuesday on a limited basis.
Willis has a groin injury and didn’t practice on Monday or Tuesday.
Not having both of them against a Rams team that was 1-0-1 against San Fran last year will be a daunting task for a team predicted by many to go to the Super Bowl.