It’s time for the NFL Week 5 picks and predictions, and there are a litany of terrific games to break down for the weekend.
As always, all lines are provided by our partners at WynnBet.
Take both these teams — and their quarterbacks — to the glue factory. It’s going to be a battle of wills … for the teams and fans.
Pick: Denver 19, Indianapolis 17
The Giants are surprising early, while the Packers are underwhelming. Yet both are 3-1, largely because Green Bay is so much more talented than most. Expect the Packers to prevail.
Pick: Green Bay 27, New York 20
Tough to see the Buccaneers losing three straight games, let alone at home. Tom Brady will significantly outplay Marcus Mariota, and that’ll be the chief difference.
Pick: Tampa Bay 26, Atlanta 13
The Vikings have a propensity to make games like this interesting, but the Bears don’t have enough firepower to win.
Pick: Minnesota 28, Chicago 15
Points will be scored. The question is who is under center for the Patriots, and can the Lions get a few key stops?
Pick: New England 30, Detroit 28
The Jaguars are showing real progress. The Texans are not. Jacksonville should handle business at home against Houston.
Pick: Jacksonville 29, Houston 17
Toughest game to pick this week. Who the hell knows? Nick Chubb might run for 200 yards.
Pick: Cleveland 24, Los Angeles 23
How much of a difference is there between Teddy Bridgewater and Tua Tagovailoa? We’re about to find out.
Pick: Miami 25, New York 23
This is going to be a ritualistic killing.
Pick: Buffalo 30, Pittsburgh 9
Why are the Saints favored by 5.5 points? They’ve been awful every game this season, while the Seahawks are 2-2 and playing really solid offense.
Pick: Seattle 24, New Orleans 22
Tennessee is back in business after winning the last two weeks, while Washington has lost three straight. Should be a close game, coming down to who makes a big mistake or two.
Pick: Tennessee 24, Washington 21
Baker Mayfield against the Niners defense. That should be put behind a pay-per-view surcharge.
Pick: San Francisco 20, Carolina 9
Can the Rams block the Cowboys? Feels like Matthew Stafford could be looking up at the SoFi Stadium roof a ton. That said, can Dallas score enough?
Pick: Los Angeles 22, Dallas 20
At some point, the Eagles are going to lose. Is this a trap game with the Cowboys next? Maybe, but tough to pick Arizona against a decent team.
Pick: Philadelphia 24, Arizona 21
Best game of the week. Whoever loses will be 2-3, while the winner has a lead in the AFC North and a critical win. I’ll take the better passing game, and better defense.
Pick: Cincinnati 34, Baltimore 30
What’s the case for Las Vegas stopping Kansas City’s offense? Just too many weapons against a defense with Maxx Crosby and little else.
Pick: Kansas City 35, Las Vegas 23
Last Week: 10-6
Season: 35-28-1