MLB Picks

Cubs vs Cardinals Game 2 Prediction and Odds for Thursday, August 4 (Fade Sean Newcomb in Return)

Iain MacMillan
Sean Newcomb will see his first action with the Cubs since June 12th.
Sean Newcomb will see his first action with the Cubs since June 12th. / Jon Durr-USA TODAY Sports

The Chicago Cubs and St. Louis Cardinals had a game postponed on Wednesday due to rain, but they don't need to wait long to make up for it.

The two NL Central rivals face-off in a double-header on Thursday. If you want to see our breakdown and pick for the first game of the double-header, check out our betting preview here.

In this article, we'll focus on the second game, which is set to begin at approximately 7:45 pm et.

Let's break down the odds, courtesy of WynnBET Sportsbook.

Cubs vs. Cardinals Game 2 Odds, Run Line, and Total

Run line:

  • Cubs +1.5 (-145)
  • Cardinals -1.5 (+120)


  • Cubs +165
  • Cardinals -180


  • 8.5 (Over -110/Under -110)

Cubs vs. Cardinals Game 2 Prediction and Pick

Sean Newcomb gets the start for the Cubs in the second game, but it's unclear if it's going to be a bullpen game, or if Newcomb will attempt his first full-length start of the season.

Whatever role he'll play, he'll be the one throwing the opening pitch and he'll hope to do better than he has so far this season. He enters the game with an 11.57 ERA, but to be fair, he's only pitched 9.1 innings. He should be able to improve on that mark in a hurry, if he can pitch well.

The bad news for him is he'll have to face a Cardinals offense that ranks ninth in OPS dating back to July 1. The Cubs likely won't give their pitchers much in terms of run support, considering they rank 25th in OPS during the same stretch.

Jose Quintana (3.50 ERA) gets the start for the Cardinals, and I'd much rather back St. Louis than the questionable pitching situation going on with Chicago today.

Lean: Cardinals -180

You can track Iain's bets on Betstamp here.