NFL Week 12 Schedule, Odds, Lines and Over/Unders (Every Team's Spread, Moneyline and Total)

Philadelphia Eagles quarterback Jalen Hurts leaps into the end zone for a game winning touchdown on the road vs. the Indianapolis Colts in Week 11.
Philadelphia Eagles quarterback Jalen Hurts leaps into the end zone for a game winning touchdown on the road vs. the Indianapolis Colts in Week 11. / Trevor Ruszkowski-USA TODAY Sports
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We've arrived at the Thanksgiving portion of the NFL schedule, as Week 12 begins with three Turkey Day matchups, following by a busy Sunday and Monday Night slate of action.

In Week 11, the favorites finally had a solid week, going 10-2 straight up (SU) and 7-5 ATS, but the season still belongs to the dogs and unders.

Before checking out all the opening odds, latest lines and movement, here are a few of this week's most notable matchups.

The Kansas City Chiefs, fresh off their remarkable comeback against the L.A. Chargers to win their 14th consecutive road game against the division, return home to face the other L.A. team in the Rams at Arrowhead Stadium.

The Chiefs are trending towards being a two-touchdown favorite with Rams quarterback Matthew Stafford in concussion protocol, but keep in mind that Kansas City has only covered once at home all season long, and that was by a half-point to the Jacksonville Jaguars in Week 9; winning by 10 with a 9.5-point spread.

Perhaps the marquee game for Sunday features the Cincinnati Bengals, fresh off their win and cover on the road vs. the Pittsburgh Steelers against the hottest against the spread (ATS) team in the NFL in the Tennessee Titans.

Tennessee has covered in eight consecutive games after going 0-2 ATS to begin the season. Interestingly enough, they open at home as a short dog vs. the Bengals.

Lastly, in the Sunday Night Football slot, the Philadelphia Eagles got a big road win to get off the schneid in Indianapolis following their disappointing home loss in Week 10 to the Washington Commanders; ending their perfect season.

While Jalen Hurts delivered the game-winning touchdown run late in the game, another unbeaten streak came to a close on Sunday for the Eagles. Up until Week 11, the first half OVER had hit in every single game until Sunday.

Looking for the latest odds solely focused on the Thanksgiving slate of games? Check out the opening numbers HERE:

NFL Week 12 Odds for Every Team, Every Game


Game odds refresh periodically and are subject to change.