2022 March Madness Opening Odds: Spreads, Moneyline and Totals for the NCAA Men's Tournament
NCAA Tournament Odds for the First Four Rounds
Indiana, Notre Dame, Rutgers and Wyoming were the last four in.
— BetSided (@BetSided) March 13, 2022
Dayton, Oklahoma, SMU, and Texas A&M are the last four out. pic.twitter.com/9HttUXMnVU
All odds are courtesy of WynnBET Sportsbook:
Tuesday, March 15
No. 16 Texas A&M Corpus Christi vs. No. 16 Texas Southern
- Texas Southern -2.5, Total: 136, ML: -170/+150
No. 12 Indiana vs. No. 12 Wyoming
- Indiana -4, Total: 132.5, ML: -180/+150
Wednesday, March 16
No. 16 Bryant vs. No. 16 Wright State
- Wright State -2 (-115), Total: 153.5, ML: -120/EV
No. 11 Notre Dame vs. No. 11 Rutgers
- Notre Dame -1, Total: 133, ML: -115/-105
NCAA Men's Tournament Opening Odds: West Region
The West Region is locked in! pic.twitter.com/sWY8Zk0xfB
— BetSided (@BetSided) March 13, 2022
No. 1 Gonzaga vs. No. 16 Georgia State
- Gonzaga -23, Total: 148.5, ML: -5000/+1500
No. 8 Boise State vs. No. 9 Memphis
- Memphis -2.5, Total: 133.5, ML: -145/+120
No. 5 Connecticut vs. No. 12 New Mexico State
- Connecticut -5.5, Total: 133.5, ML: -220/+180
No. 4 Arkansas vs. No. 13 Vermont
- Arkansas -4, Total: 140, ML: -200/+165
No. 3 Texas Tech vs. No. 14 Montana State
- Texas Tech -14.5, Total: 131, ML: -1400/+800
No. 7 Michigan State vs. No. 10 Davidson
- Michigan State -1.5, Total: 140, ML: -125/+105
No. 2 Duke vs. No. 15 California State Fullerton
- Duke -17, Total: 143, ML: -2000/+1000
NCAA Men's Tournament Opening Odds: East Region
Baylor secures the No. 1 seed in the East Region. pic.twitter.com/oOnUvz5D0f
— BetSided (@BetSided) March 13, 2022
No. 1 Baylor vs. No. 16 Norfolk State
- Baylor -20, Total: 137.5, ML: -5000/+1500
No. 8 North Carolina vs. No. 9 Marquette
- North Carolina -4, Total: 151.5, ML: -180/+150
No. 4 UCLA vs. No. 13 Akron
- UCLA -15.5 (EV), Total: 129, ML: -1200/+750
No. 6 Texas vs. No. 11 Virginia Tech
- Texas -1.5 (-115), Total: 125.5, ML: -120/+EV
No. 3 Purdue vs. No. 14 Yale
- Purdue -14.5, Total: 143, ML: -1400/+800
No. 7 Murray State vs. No. 10 San Francisco
- San Francisco -1, Total: 138.5, ML: -120/EV
No. 2 Kentucky vs. No. 15 St. Peter’s
- Kentucky -16, Total: 133, ML: -1600/+900
NCAA Men's Tournament Opening Odds: South Region
The South Region is loaded with intriguing matchups. pic.twitter.com/3fZrc3sdqs
— BetSided (@BetSided) March 13, 2022
No. 8 Seton Hall vs. No. 9 TCU
- Seton Hall -1 (-115), Total: 129, ML: -115/-105
No. 5 Houston vs. No. 12 UAB
- Houston -8.5 (-115), Total: 136.5, ML: -360/+280
No. 4 Illinois vs. No. 13 Chattanooga
- Illinois -6.5 (-120), Total: 136.5, ML: -300/+240
No. 6 Colorado State vs. No. 11 Michigan
- Michigan -2.5 (-105), Total: 139.5, ML: -145/+120
No. 3 Tennessee vs. No. 14 Longwood
- Tennessee -16.5 (-115), Total: 133, ML: -1600/+900
No. 7 Ohio State vs. No. 10 Loyola Chicago
- Loyola Chicago -1, Total: 133, ML: -135/+112
No. 2 Villanova vs. No. 15 Delaware
- Villanova -16.5 (-105), Total: 133, ML: -1400/+800
NCAA Men's Tournament Opening Odds: Midwest Region
Thoughts on the Midwest Region? pic.twitter.com/bclea3fVfv
— BetSided (@BetSided) March 13, 2022
No. 8 San Diego State vs. No. 9 Creighton
- San Diego State -2.5 (-105), Total: 121, ML: -145/+120
No. 5 Iowa vs. No. 12 Richmond
- Iowa -9.5, Total: 151.5, ML: -425/+325
No. 4 Providence vs. No. 13 South Dakota State
- Providence -2.5, Total: 148.5, ML: -125/+105
No. 6 LSU vs. No. 11 Iowa State
- LSU -5, Total: 127.5, ML: -210/+170
No. 3 Wisconsin vs. No. 14 Colgate
- Wisconsin -7, Total: 139.5, ML: -300/+240
No. 7 USC vs. No. 10 Miami
- USC -1 (-120), Total: 141.5, ML: -125/+105
No. 2 Auburn vs. No. 15 Jacksonville State
- Auburn -16, Total: 139, ML: -1600/+900
Follow BetSided's March Madness hub throughout the entirety of the NCAA men's and women's tournaments for full betting previews and picks for every game, updated betting odds futures for the Final Four and national championship, insights, trends, videos, podcasts and more!