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49ers vs. Eagles: Odds, Spread, Over/Under and Prediction for NFL Week 2

By Iain MacMillan

Deebo Samuel had nine catches for 189 yards in the San Francisco 49ers Week 1 matchup against the Detroit Lions.
Deebo Samuel had nine catches for 189 yards in the San Francisco 49ers Week 1 matchup against the Detroit Lions. / David Reginek-USA TODAY Sports
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The San Francisco 49ers were one of the most bet on teams in Week 1 of the NFL season, so much so that the line moved from 7.5 to 8.5 last week before kickoff on Sunday. As a result, 49ers backers were victim to the first bad beat of the NFL season.

The Detroit Lions scored 16-unanswered points late in the 4th quarter which included two successful two-point conversions and a recovered onside kick. The late onslaught of points caused the Lions to lose by only eight points, ruining the day of any bettor who had the 49ers at the -8.5 spread.

The 49ers now take on the Philadelphia Eagles in Week 2 action. The Eagles are coming off an underdog win against the Atlanta Falcons in which they closed as 3.5-point ‘dogs.

The Eagles faced the 49ers last season on Sunday Night Football in Week 4. Philadelphia pulled the upset in that one, beating San Francisco as massive 8.5-point underdogs, 25-20.

49ers vs. Eagles Spread, Odds, and Over/Under

Spread:

49ers -3.5 (-110)

Eagles +3.5 (-110)

Moneyline:

49ers -190

Eagles +160

Total:

50 (OVER -110/UNDER -110)

49ers vs Eagles Prediction and Pick

The 49ers defense may not be as good as we all thought. Or at least, if Week 1 is any indication.

The Detroit Lions, the team that was supposed to be one of the worst in the NFL, put up 430 yards and 33 points against this 49ers team. Is that an anomaly game or is it a sign that the 49ers defense isn't all that it’s cracked up to be?

I backed the Eagles in Week 1 against my Falcons, and I’m back on them again in Week 2 to cover the 3.5 point spread. I feel Jalen Hurts is one of the most underrated quarterbacks in the NFL, and he looked fantastic in Week 1, throwing for 264 yards, three touchdowns, and no interceptions.

Meanwhile, Atlanta wasn’t able to get in the end zone once all game, scoring only six points.

If the spread was below the magic number of three, I’d consider taking Kyle Shanahan and the 49ers, but at 3.5, give me the home underdog.

Make your pick now with the WynnBET app.

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