49ers vs. Falcons Prediction, Odds, Spread and Over/Under for NFL Week 6

San Francisco 49ers defensive end Nick Bosa (97).
San Francisco 49ers defensive end Nick Bosa (97). / Kyle Terada-USA TODAY Sports
facebooktwitterreddit

The San Francisco 49ers, for the second straight week, are a huge favorite over an NFC South team. The 49ers just demolished the Carolina Panthers, and look to do the same against the Atlanta Falcons. 

This season has started off much better for the Falcons than many people thought it would. They are 2-3 on the season and have been one of the best running teams in the league. However, the 49ers look on track for another deep playoff run. Can they have another dominant win this week?

 

49ers vs. Falcons Spread, Odds and Over/Under

49ers vs. Falcons Betting Trends

  • San Francisco has covered in each of its wins this season
  • The 49ers are 5-1 ATS in their last six games as at least a 6-point favorite
  • The Falcons are 5-0 ATS this season
  • Atlanta has hit the UNDER in its last two games 

49ers vs. Falcons Prediction and Pick

The Falcons were able to score in garbage time and backdoor cover against the Buccaneers, but don’t let that fool you into backing them this week against San Francisco. 

I’m all over the 49ers in this game, as they are perfectly designed to stop the Falcons. Atlanta makes its money off of the running game. It’s sixth in yards per rush, fourth in rushing attempts per game and third in rushing yards per game. 

San Francisco, on the other hand, is first in opponent yards per rush (3.0) and second in opponent rushing yards per game. This is a strength on strength matchup, and I’ll easily back the 49ers. 

Atlanta just faced a defense built to stop the run in Tampa Bay, and we saw the giant lead the Bucs were able to get out to. Now, they’ll have to face a better defense with more weapons on the offensive side of the ball. 

As long as everyone stays healthy, the 49ers should dominate on the ground – on both offense and defense – and cruise to another win.


You can find Donnavan Smoot’s full betting record here.

Game odds refresh periodically and are subject to change.