49ers vs. Seahawks Updated Odds and Prediction: What Bettors Need to Know

The San Francisco 49ers are making a run towards the playoffs and this week will be a crucial game on that path. They'll travel to face the Seattle Seahawks and try and move to 7-5 and possibly second in the NFC West.

The Seahawks won the first matchup back in October, but the 49ers are in a much better position than they were two months ago. Can they get their revenge?

Here are the odds for their matchup via WynnBET.

49ers vs. Seahawks Updated Spread, Odds and Over/Under

Spread: 

• 49ers: -3.0 (+100)
• Seahawks: +3.0 (-120)

Moneyline: 

• 49ers: -165
• Seahawks: +145

Total:

• 45.0 (Over: -110/Under: -110)

Seahawks vs. 49ers Betting Trends

• The 49ers are 5-6 against the spread this season.
• The Seahawks are 5-5 against the spread this season.
• Seattle is just 1-2 against the spread in games vs. division opponents this season. 
• The OVER is 6-5 in San Francisco’s 11 games this season.

49ers vs. Seahawks Prediction and Pick

Earlier this week, BetSided’s Peter Dewey picked the 49ers to cover. However, that was when the 49ers were 2.5-point favorites. 

San Francisco has won three straight and is just a game back of the Los Angeles Rams for the second spot in the NFC West. Seattle does have Russell Wilson back, but it has lost back-to-back games heading into a Monday Night Football matchup with the Washington Football Team. I like the 49ers at less than a field goal on the road against a Seattle team that may not have much to play for.

The Seahawks are in a freefall this season and seem destined for a breakup with Russell Wilson. They are trending the wrong way, while the 49ers just got a good win against the Vikings and are positioning themselves in the playoff race.

I’ll take San Francisco even if the line moved to -3.

Pick: 49ers -3.0 (-110)