Best NFL Prop Bets for Jaguars vs. Colts in Week 6 (Fade Matt Ryan In Divisional Matchup)

Oct 6, 2022; Denver, Colorado, USA; Indianapolis Colts quarterback Matt Ryan (2) scrambles under
Oct 6, 2022; Denver, Colorado, USA; Indianapolis Colts quarterback Matt Ryan (2) scrambles under / Isaiah J. Downing-USA TODAY Sports
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The Colts play for the first time since their overtime win against the Broncos in Week 5. They come into this game 2-2-1, with a chance to get revenge on the Jaguars and potentially get up to first place in the AFC South. 

There’s a lot on the line in the game, so let’s break it down from a player prop perspective.

Here are three prop bets to bet for Jaguars-Colts

Best Prop Bets For Jaguars-Colts

  • Christian Kirk OVER 54.5 Receiving Yards (-115)
  • Matt Ryan UNDER 242.5 Passing Yards (-125)
  • Travis Etienne OVER 36.5 Rushing Yards (-113)

Christian Kirk OVER 54.5 Receiving Yards (-115)

Kirk has missed this line in consecutive games and had his worst game of the season last week. That’s exactly why we can buy low on his line. He’s still seeing nearly 8 targets per game and is averaging 67.6 yards per game. The strength of the Colts’ defense is the running game. The passing game can be attacked and that’s what Krik will do.

Matt Ryan UNDER 242.5 Passing Yards (-125)

Ryan has cleared this line in the last two games, but it is clear that he is on the last legs of his career. The Jaguars only allow 215.6 passing yards per game right now. They are also creeping up on the top 10 in yards per pass. They’ll need to step up just a little more, but Ryan’s weapons and arm don’t inspire too much confidence for me.

Travis Etienne OVER 36.5 Rushing Yards (-113)

Etienne has been the more consistent runner out of James Robinson and him, and he has the lower number to get to. Etienne has cleared this line in three of the five games this season. He’s coming off his best game of the season and is in line for another game full of touches. The Colts have one of the best run defenses in the league, so don’t expect Etienne to go for 100 yards, but 37 yards is reasonable. 


Game odds refresh periodically and are subject to change.