Bills vs. Chiefs Prediction, Odds, Spread and Over/Under for NFL Week 6 (Buffalo Will Avenge Divisional Round Loss)

Bills quarterback Josh Allen heads off the field after a 42-36 overtire loss to the Chiefs knocked
Bills quarterback Josh Allen heads off the field after a 42-36 overtire loss to the Chiefs knocked / JAMIE GERMANO/ROCHESTER DEMOCRAT AND

Week 6 of the NFL will give us our yearly viewing of Josh Allen vs. Patrick Mahomes, which always delivers as must-watch television.

It's a shame that the game isn't in prime time, but at least with it being in the late-afternoon slot, we can divert most of our attention toward it. This will hopefully be a matchup we'll see for years to come, and this season's edition of it will be a rematch of last year's AFC Divisional Round, which was one of the best playoff games in recent memory.

The Bills scored to go up on the Chiefs with 13 seconds left in the game, but Kansas City stormed back to kick a game-winning field goal as time expired.

Will Josh Allen and company get their revenge on Sunday? Let's take a look at what the oddsmakers think.

Bills vs. Chiefs Odds, Spread, and Total

Bills vs. Chiefs Betting Trends

  • The UNDER is 4-1 in Bills games this season
  • The UNDER is 3-0 in Bills roads games this season
  • Chiefs are 6-2 ATS in last eight games against Bills
  • The OVER is 3-0 in last three meetings between teams

Bills vs. Chiefs Prediction and Pick

The Bills and the Chiefs are the kings of the AFC, but I don't think there's any doubt that Buffalo is the better team this season.

They lead in the NFL in yards per play at 6.7, while also giving up only 4.4 yards per play, which is the second best mark in the NFL. Any time you're going to set the line at less than three points, I'm obligated to back the Bills with how dominant they've been.

They're also first in third down conversion percentage, getting a first down on 55.74% of their third downs. They also rank third in yards per pass attempt, and now take on a Chiefs team that ranks 31st in opponent completion percentage.

As long as the line stays under three points, I'm all over Buffalo in this spot.

Game odds refresh periodically and are subject to change.