Bills vs. Panthers Prediction, Odds, Spread and Over/Under for NFL Preseason Week 3 (Bills Too Good in Preseason)

It's official: Baker Mayfield is the starting quarterback of the Carolina Panthers.

Mayfield didn't play in last week's loss to the Patriots, but it's officially his team. It's unclear yet if he'll play against the Buffalo Bills in NFL Preseason Week 3, though Buffalo is such a dominant preseason team that it doesn't matter either way.

Buffalo won and covered the spread in each of it's last 10 preseason games, looking dominant in a 42-15 victory over the Broncos last week.

Can the Bills stay hot or will Carolina pick up a win on the news that Mayfield is the man moving forward?

Let's check out the consensus odds to find out:

Bills vs Panthers Odds, Spread and Total

Spread

• Bills +6 (-110)
• Panthers -6 (-110)

Moneyline:

• Bills: +240
• Panthers: -300

Total:

• 38.0 (Over -110/Under -110)

Bills vs Panthers Betting Trends

Bills

• 10-0 ATS last 10 preseason games

• OVER is 8-2 last 10 preseason games

• 9-0 outright last nine preseason games as underdogs

Panthers

• 7-5-1 ATS last 13 preseason games

• OVER is 11-5-1 last 17 preseason games

• 5-4-1 ATS last 10 preseason games as favorites

Bills vs Panthers Prediction and Pick

I've seen nothing to suggest the Bills should be such large underdogs to the Panthers. Honestly, if the Panthers play their starters the entire game while the Bills just play backups, Buffalo would still have value.

Sean McDermott is a significantly better coach than Matt Rhule, and the Bills have a much, much deeper roster. I'm not sure what Buffalo does differently in the preseason than everyone else besides the Ravens, but this is as dominant a preseason team as we've seen in recent years. It's a gift to get a +6 spread.

If the Bills' starters play even a single play, this line is a gigantic miscalculation on sportsbooks' end. Even if they don't, Buffalo is too good and too well-coached to support the odds here.

I don't have faith in Carolina this season, nor do I believe Baker Mayfield is good. Therefore, I'm happily betting the Bills. I'll put a full unit on the spread and a half-unit on the +240 moneyline odds. With the Buffalo winning nine consecutive preseason games as underdogs, the value is too much to ignore.

Pick: Full Unit on Bills +6 (-110), Half-Unit on Bills (+240)

Follow all of Joe Summers' betting picks here.