Buccaneers vs. Panthers Prediction, Odds, Against Spread and Over/Under for NFL Week 16

The Buccaneers will face the Panthers in NFL Week 16 action.
The Buccaneers will face the Panthers in NFL Week 16 action. / Nathan Ray Seebeck-USA TODAY Sports

The Tampa Bay Buccaneers lost to the New Orleans Saints as sizable favorites for the second time this season, this time the loss came as 11-point home favorites. They now shift gears and get ready to take on another NFC South opponent in the Carolina Panthers.

The Panthers have yet to be mathematically eliminated, but their season is virtually over as they've struggled to find any sort of offensive rhythm all season. Star running back Christian McCaffrey has hardly played all year due to injuries, and the Panthers haven't found any consistent quarterback play from Sam Darnold, Cam Newton, or PJ Walker.

Let's take a look at the odds for this divisional battle via WynnBET Sportsbook.

Buccaneers vs. Panthers Odds, Spread, and Total


  • Buccaneers -11 (-110)
  • Panthers +11 (-110)


  • Buccaneers -500
  • Panthers +400


  • 44 (Over -110/Under -110)

Buccaneers vs. Panthers Betting Trends

  • Buccaneers are 4-1 ATS in their last five games.
  • The UNDER is 6-3 in the Bucs last nine games.
  • Buccaneers are 4-1 ATS in their last five games against the Panthers.
  • Panthers are 1-5 ATS in their last six games
  • Panthers are 0-5 ATS in their last five home games.

Buccaneers vs. Panthers Prediction and Odds

The Panthers, especially their offense, is a dumpster fire and they've seemingly given up on the season. Don't allow the Buccaneers latest result to cloud your judgement. They are still one of the top teams in the NFL. They rank third in yards per play (6) and sixth in opponent yards per play (5.2).

Meanwhile, the Panthers offense has been abysmal all season and have somehow gotten worse in recent weeks. They rank 31st in yards per play (4.7), and they've only averaged 4.3 yards per play over their last three games.

I have zero faith that the Panthers offense can keep pace with the Buccaneers offense, despite the season-ending injury to Tampa Bay wide receiver Chris Godwin.

Pick: Buccaneers -11