Cardinals vs. Seahawks Prediction, Odds, Against Spread and Over/Under for NFL Week 11

The Arizona Cardinals lost to the Carolina Panthers in Week 10, 31-10, as Colt McCoy couldn’t carry over his impressive performance against the San Francisco 49ers from the week prior. Not only did McCoy struggle at times against the Panthers, Carolina knocked McCoy out of the game late in the third quarter. Chris Streveler would take over as signal caller in McCoy’s absence.

Arizona is crossing their collective fingers that Kyler Murray is healthy for Week 11’s matchup with the Seattle Seahawks. McCoy is questionable with a pec injury so, the Cardinals could start Streveler in Week 11.

The Seahawks got shutout by the Green Bay Packers last week, 17-0. It was the first shutout that Seattle endured in Russell Wilson’s career.

Wilson only completed 20 of 40 passes for 161 yards and two interceptions in the loss, as the entire Seattle offense came to a halt against the Packers’ defense. 

Here are the odds for this NFC West matchup, courtesy of WynnBET Sportsbook.

Cardinals vs. Seahawks Odds, Spread, and Total

Spread:

• Cardinals -2.5 (-110)
• Seahawks +2.5 (-110)

Moneyline:

• Cardinals -130
• Seahawks +110

Total:

• 50 (Over -110/Under -110)

Cardinals vs. Seahawks Betting Trends

• Arizona is 7-3 against the spread this season.
• Seattle is 5-4 against the spread this season.
• The Cardinals are 5-0 ATS in their last five games following a straight up loss of more than 14 points.
• The Under is 6-0 in the Seahawks' last six games as an underdog.
• The Under is 7-0 in the Cardinals' last seven games as a road favorite.

Cardinals vs. Seahawks Prediction and Pick

Seattle’s offense has been inconsistent this season, and at times, it’s been downright messy. It’s hard to back the Seahawks offense to get back on track against one of the NFL’s best defenses in Arizona. 

Seattle’s defense has also been messy, currently 31st in the NFL in total yards allowed, 29th in passing yards allowed, and 25th in rushing yards allowed. A potentially explosive Cardinals offense could be a nightmare for the Seahawks in Week 11. 

If Kyler Murray is healthy, the Cardinals will have a decent chance to pick up a win over their NFC West rivals. But, if Murray struggles to get back in the swing of things, it could slow down Arizona’s offense.

With both of these offenses being surrounded with question marks, the best bet for this game is to focus on the total.

Pick: Under 50