Cardinals vs. Seahawks Updated Odds and Prediction: What Bettors Need to Know

Russell Wilson and the Seahawks need a win badly.
Russell Wilson and the Seahawks need a win badly. / Benny Sieu-USA TODAY Sports
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The Seattle Seahawks are looking to get back into the playoff picture now that Russell Wilson is healthy. To do so, they will have to beat the NFC West-leading Arizona Cardinals at Lumen Field. NFC West matchups are always hard fought and that won’t change regardless of who’s at quarterback for the Cardinals. 

Both teams are coming off of big losses and need a win to get back on track. 

Here are the odds for their matchup via WynnBET.

Cardinals vs. Seahawks Updated Spread, Odds and Over/Under

Spread: 

  • Cardinals: -2.0 (-110)
  • Seahawks: +2.0 (-110)

Moneyline: 

  • Cardinals: -125
  • Seahawks: +105

Total:

  • 48.5 (Over: -110/Under: -110)

Cardinals vs. Seahawks Betting Trends

  • Arizona is 7-3 ATS this season. 
  • Seattle hasn’t covered in three straight games. 
  • The Seahawks are 15-9 as a home underdog in Pete Carrol’s tenure.
  • The Cardinals are 3-2 SU as an away favorite since 2019.

Cardinals vs Seahawks Prediction and Pick

Earlier this week, BetSided’s Thomas Snodgrass decided to make his pick on this game not focused on the moneyline. 

“If Kyler Murray is healthy, the Cardinals will have a decent chance to pick up a win over their NFC West rivals. But, if Murray struggles to get back in the swing of things, it could slow down Arizona’s offense.

"With both of these offenses being surrounded with question marks, the best bet for this game is to focus on the total.”

The Cardinals clearly aren’t the same team without Murray in the lineup. If he’s out, I’ll take Seattle. However if he plays, I’ll take Arizona to pick up the win and stay on top of the NFC West. 

Pick: Cardinals ML (-125)


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