Colts vs. Cowboys Prediction and Odds for NFL Week 13 (Cowboys Defense Will Feast on Colts Offensive Line)

Nov 24, 2022; Arlington, Texas, USA; Dallas Cowboys linebacker Micah Parsons (11) celebrates after
Nov 24, 2022; Arlington, Texas, USA; Dallas Cowboys linebacker Micah Parsons (11) celebrates after / Jerome Miron-USA TODAY Sports
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If someone can explain to me why the NFL didn't flex out the this week's Sunday Night Football game, I'd greatly appreciate it. We unfortunately will be subjected to the torture that is the Indianapolis Colts in prime time once again.

After looking miserable in their 24-17 loss to the Pittsburgh Steelers on Monday night, they'll head to Texas to take on the Dallas Cowboys.

Let's dive into the odds for this game and then I'll give you my best bet.

Colts vs. Cowboys Odds, Spread, and Total

Colts vs. Cowboys Betting Trends

  • Colts are 2-4 ATS in their last six games
  • The UNDER is 14-3 in the Colts' last 17 games
  • Colts are 9-3 ATS in their last 12 games against NFC opponents
  • Cowboys are 7-3 ATS in their last 10 games
  • The UNDER is 4-1 in the last five meetings between these two teams
  • Cowboys are 10-5 ATS in their last 15 games against AFC South opponents
  • Cowboys are 7-0 ATS in their last seven games played in December

Colts vs. Cowboys Prediction and Pick

I am seriously concerned for the Matt Ryan's health in this game. The Colts offensive line ranks 28th in QB sacked percentage, allowing their QB to get sacked on 8.85% of his drop backs.

Now, they have to face the best pass rush in the NFL. The Cowboys are sacking the opposing QB on 11.51% of passing plays. That's an insane rate, and now they'll get to feast against the Colts and one of the most immobile quarterbacks in the game in Matt Ryan.

The Colts defense as a whole is atrocious, ranking 27th in yards per play. We saw how they did against the Steelers, who have a bottom 10 defense, and now they have to face arguably the best defense in the NFL.

This game is going to be ugly to watch and I think the Cowboys defense will carry them to a double-digit victory.

You can track Iain's bets on Betstamp here.


Game odds refresh periodically and are subject to change.