Daily Dinger: Best Home Run Prop Bet Picks for Thursday, April 21 (Back Killer B's of Bo, Byron and Bryan)

Toronto Blue Jays infielder Bo Bichette is close to turning the corner on getting his power swing going in 2022.
Toronto Blue Jays infielder Bo Bichette is close to turning the corner on getting his power swing going in 2022. / Mark Blinch/GettyImages

Over the 2022 season, the BetSided team of editors debate and share our best home run prop bet picks of the day in Major League Baseball.

WynnBET Sportsbook offers home run odds for several players in each MLB matchup, but not all players mentioned in the article are always available. Bettors can still wager on all these games as well as take advantage of several other unique prop bet opportunities.

Odds shown are consensus.

Best Home Run Picks for Thursday, April 21

  • Joc Pederson (+455) at WynnBET
  • Bo Bichette (+600)
  • Byron Buxton (+240)
  • Bryan Reynolds (+480) at WynnBET

Joc Pederson (+455) - San Francisco Giants vs. New York Mets

Pederson has already hit three home runs this season and has a solid matchup against Carlos Carrasco today.

All three of Pederson’s homers have been against right-handed pitchers. He's also been pretty consistent getting a home run every couple of games – not going more than three games without one.

If he sticks to this pattern, a baseball might be flying out of Citi Field. -- Donnavan Smoot

Bo Bichette (+600) - Toronto Blue Jays vs. Boston Red Sox

It’s been a slow start to the 2022 season for Toronto Blue Jays shortstop Bo Bichette, but he has a chance to turn things around on Thursday against a pitcher he fared well against last season.

Bichette takes on Boston Red Sox starter Tanner Houck, who is 2-for-4 with an RBI against in his career. The Red Sox and Jays haven’t exactly played the high-scoring games that many of us expected, but I think that could change today.

Houck has yet to allow a homer this year, but Bichette’s power to left field could be on display with the Green Monster making it a little easier to go yard. -- Peter Dewey

Byron Buxton (+240) - Minnesota Twins vs. Kansas City Royals

Boy have the Twins missed Byron Buxton.

Since going down on the 15th of April with a knee injury, Minnesota's offense has completely vanished. With the exception of their eight runs on Patriots' Day Monday afternoon in Boston, they've scored a total of five runs in four games.

He returns to the lineup in the 1-spot as the DH and faces Zack Greinke, who misses no bats in the twilight stage of his career. He's recorded just one strikeout through 11 innings pitched; and if Buxton makes contact, he hits it HARD: 100th percentile in hard-hit exit velocity and barrel percentage via MLB Statcast.

Via Ballpark Pal, Buxton is also Greinke's most difficult matchup today.

I like him to launch one in his return to the field on a gorgeous day in Kansas City. -- Ben Heisler

Bryan Reynolds (+480) - Pittsburgh Pirates vs. Chicago Cubs

Bryan Reynolds has already hit two home runs this season, and I think he gets his third tonight against the Cubs.

The Pirates face Mark Leiter Jr., who gave up seven earned runs in his first start, lasting just 3.1 innings. He also gave up 2.7 home runs per nine innings his last season in the Majors, so this is a guy who can give up dingers.

I'll back Reynolds to go yard tonight. -- Iain MacMillan

Follow along with our updated Daily Dinger record for the season HERE