Falcons vs. 49ers Prediction, Odds, Against Spread and Over/Under for NFL Week 15

The 49ers are set to host the Falcons in a battle between teams that are firmly in the hunt for the playoffs.
The 49ers are set to host the Falcons in a battle between teams that are firmly in the hunt for the playoffs. / Sam Greene/The Enquirer / USA TODAY

The Atlanta Falcons and San Francisco 49ers will face-off in Week 15 in a battle between two teams who are vying for a spot in the NFC playoffs.

The 49ers are in sole possession of the No. 6 spot, while the Falcons are in a five-way tie for the seventh and final seeding in the postseason. If the Falcons are able to pull off an upset win, they could put themselves in the driver seat for the seventh seed with winnable games against the Lions and Saints still left on their schedule.

Here are the odds via WynnBET for this NFC showdown.

Falcons vs. 49ers Odds, Spread, and Total


  • Falcons +8.5 (-110)
  • 49ers -8.5 (-110)


  • Falcons +320
  • 49ers -400


  • 45.5 (Over -110/Under -110)

Falcons vs. 49ers Betting Trends

  • Falcons are 5-1 ATS in their last six road games.
  • The OVER is 10-3 in the Falcons last 13 games vs. NFC opponents.
  • 49ers are 4-1 ATS in their last five games.
  • 49ers are 3-8 ATS in their last 11 games vs. NFC South opponents.

Falcons vs. 49ers Prediction and Pick

Arthur Smith deserves a lot of credit for having the Falcons in contention for a playoff spot in Week 15 of the NFL season, but Atlanta is overmatched when they take on truly superior opponents. They're 0-4 straight up and against the spread when playing teams with a winning record this season.

The 49ers are seventh in yards per play this season and 12th in opponent yards per play, which firmly puts them in the top third of teams in the NFL. That spells trouble for a Falcons team that ranks in the bottom 10 in both of those categories.

Look for the 49ers defensive line to have a field day against a Falcons offensive line that has struggled all season. The 49ers rank sixth in sack percentage, recording a sack on 7.3% of their opponent drop backs.

I refuse to bet on the Falcons when they play a superior opponent, and that's exactly what the 49ers are.

Pick: 49ers -8.5