MLB Probable Pitchers for Wednesday, September 21 (Who's Starting for Every MLB Team Today?)

San Diego Padres starting pitcher Blake Snell.
San Diego Padres starting pitcher Blake Snell. / Orlando Ramirez-USA TODAY Sports
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Two more teams clinched playoff spots in Major League Baseball on Tuesday night, as the New York Mets and Atlanta Braves punched their tickets with wins, keeping the NL East division race as tight as ever. 

Both of those teams play afternoon matchups on Wednesday, and we have the pitching matchups for those games and the rest of the MLB slate on Sept. 21. 

With so many teams either on the brink of clinching or elimination, knowing these matchups is crucial before betting on MLB. Let’s jump into Wednesday’s starters: 

Washington Nationals vs. Atlanta Braves Probable Pitchers

  • Nationals: Paolo Espino
  • Braves: Bryce Elder

New York Mets vs. Milwaukee Brewers Probable Pitchers

  • Mets: Taijuan Walker
  • Brewers: Adrian Houser

Houston Astros vs. Tampa Bay Rays Probable Pitchers

  • Astros: Lance McCullers
  • Rays: Corey Kluber

Chicago Cubs vs. Miami Marlins Probable Pitchers

  • Cubs: Marcus Stroman
  • Marlins: Jesús Luzardo

Boston Red Sox vs. Cincinnati Reds Probable Pitchers

  • Red Sox: Connor Seabold
  • Reds: Chase Anderson 

Toronto Blue Jays vs. Philadelphia Phillies Probable Pitchers

  • Blue Jays: Kevin Gausman
  • Phillies: Zack Wheeler

Detroit Tigers vs. Baltimore Orioles Probable Pitchers

  • Tigers: Matt Manning
  • Orioles: Jordan Lyles

Pittsburgh Pirates vs. New York Yankees Probable Pitchers

  • Pirates: Roansy Contreras
  • Yankees: Luis Severino

Los Angeles Angels vs. Texas Rangers Probable Pitchers

  • Angels: Tucker Davidson
  • Rangers: Dane Dunning

Minnesota Twins vs. Kansas City Royals Probable Pitchers

  • Twins: Bailey Ober
  • Royals: Daniel Lynch

Cleveland Guardians vs. Chicago White Sox Probable Pitchers

  • Guardians: Triston McKenzie
  • White Sox: Lance Lynn

San Francisco Giants vs. Colorado Rockies Probable Pitchers

  • Giants: Logan Webb
  • Rockies: German Marquez

St. Louis Cardinals vs. San Diego Padres Probable Pitchers

  • Cardinals: Miles Mikolas
  • Padres:  Blake Snell

Seattle Mariners vs. Oakland Athletics Probable Pitchers

  • Mariners: Robbie Ray
  • A’s: James Kaprielian

Arizona Diamondbacks vs. Los Angeles Dodgers Probable Pitchers

  • Diamondbacks: Madison Bumgarner
  • Dodgers: Dustin May

Find Peter Dewey’s full betting record here.