Monday Night Football Best Anytime TD Scorer Picks for 49ers vs. Cardinals

Arizona Cardinals running back James Conner.
Arizona Cardinals running back James Conner. / Bob Donnan-USA TODAY Sports
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Monday Night Football brings us an NFC West showdown between the San Francisco 49ers and Arizona Cardinals. 

Primetime matchups are perfect for prop bets and anytime touchdown scorer picks, so why not dive into three anytime touchdown picks in this matchup?

Here are my three favorites: 

Best Best Anytime TD Scorer Picks for 49ers vs. Cardinals

  • James Conner (-120)
  • DeAndre Hopkins (+115)
  • Christian McCaffrey (-140)

James Conner (-120)

James Conner got back on track with two rushing scores last week for Arizona, and he could have a big game in Week 11 with Kyler Murray potentially out. 

The Cardinals waived running back Eno Benjamin, which is a sign that they are good with Conner’s health and him handling a major workload. 

After scoring a ton of touchdowns last season, Conner is a solid bet to find the end zone on Monday night. 

DeAndre Hopkins (+115)

DeAndre Hopkins has been a target hog since returning to the Cardinals’ lineup, receiving 13-plus targets in three of his four games. 

Even if Colt McCoy gets the start in this game, I think Hopkins goes off, especially since he made 10 grabs for 98 yards with McCoy under center last week. 

Hopkins has two scores on the season, and the Cardinals are going to involve him heavily, especially with Hollywood Brown out once again.  

Christian McCaffrey (-140)

Yes, we have to lay some juice on this prop with Christian McCaffrey, but it’s worth it when you consider that he’s scored three times in three games with the 49ers. 

CMC is going to only see his role expand as he gets to know the offense more, especially in the red zone. 

McCaffrey saw 18 touches in his last game and 26 in his second game with the 49ers. With all of those looks, the league’s best running back is bound to find paydirt.

Find Peter Dewey’s full betting record here.


Game odds refresh periodically and are subject to change.