Monday Night Football Best Prop Bets for Rams vs. 49ers (Jimmy G Poised for Bounce Back Performance)

San Francisco 49ers quarterback Jimmy Garoppolo.
San Francisco 49ers quarterback Jimmy Garoppolo. / Isaiah J. Downing-USA TODAY Sports
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The Los Angeles Rams and San Francisco 49ers will go to war on Monday Night Football in an NFC West showdown.

Jimmy Garoppolo will look to rebound after a poor performance on Sunday Night Football against the Denver Broncos last week. Meanwhile, the Rams will be looking to improve to 3-1 on the season.

Let's take a look at a few of my favorite prop bets for the final NFL game of Week 4.

Monday Night Football Best Prop Bets for Rams vs. 49ers

  • Jimmy Garoppolo OVER 225.5 Passing Yards (-102)
  • Cam Akers UNDER 42.5 Rushing Yards (-130)
  • Deebo Samuel OVER 89.5 Rushing + Receiving Yrds (-114)

Jimmy Garoppolo OVER 222.5 Passing Yards (-105)

Jimmy Garoppolo had a terrible start against the Denver Broncos on Sunday Night Football last week, but I don't expect that to be the norm moving forward.

This is a guy who averaged 254 passing yards per game last season, and he led the NFL in yards per completion at 12.7. I think this is a great buy low spot on Garoppolo's passing totals ahead of Monday night.

Cam Akers UNDER 42.5 Rushing Yards (-115)

Cam Akers had a great game against the Cardinals last week, rushing for 61 yards on 12 carries, but he'll have a much tougher test against the 49ers defense. San Francisco ranks third in the NFL in opponent yards per carry, keeping teams to average just 2.8 yards per rush.

I'll bank on the 49ers stopping Cam Akers in this one.

Deebo Samuel OVER 89.5 Rushing + Receiving Yrds (-114)

Deebo Samuel has only had one "true" Deebo Samuel-esque game this season, when he rushed for 53 yards and also racked up 44 years through the air. I think we could see another similar performance on Monday night, when he and the 49ers take on a Rams defense that has taken a step back compared to last season.

The Rams are 14th in opponent yards per play through the first three weeks. A huge gap from 2021 when they were a top five defense.