NFL Picks Against the Spread for Every Team in Week 12

Dec 19, 2021; East Rutherford, New Jersey, USA; Dallas Cowboys quarterback Dak Prescott (4) rolls
Dec 19, 2021; East Rutherford, New Jersey, USA; Dallas Cowboys quarterback Dak Prescott (4) rolls / Vincent Carchietta-USA TODAY Sports

All 32 NFL teams are in action for Thanksgiving week, giving us 16 games to wager on!

If you're looking for NFL picks against the spread, you've come to the right place. In this article, I'll give you my spread bet for every single game set to take place in Week 12, including the three games scheduled for Thanksgiving Day.

Also, if you want my best bet for each game including spreads and totals, be sure to check out this week's episode of the Bacon Bets Podcast.

Let's go through every game on the board and pick some winners against the spread!

NFL Week 12 Spread Bets

Buffalo Bills vs. Detroit Lions

  • Pick: Bills -9.5

New York Giants vs. Dallas Cowboys

  • Pick: Cowboys -9.5

The Cowboys have already beat the Giants once this season and that was with Cooper Rush at quarterback. Their offense has exploded over their last three games and I expect them to dispose of the Giants with ease on Thanksgiving.

New England Patriots vs. Minnesota Vikings

  • Pick: Patriots +2.5

Chicago Bears vs. New York Jets

  • Pick: Jets -4.5

Houston Texans vs. Miami Dolphins

  • Pick: Dolphins -13

Tampa Bay Buccaneers vs. Cleveland Browns

  • Pick: Browns +3.5

Denver Broncos vs. Carolina Panthers

  • Pick: Broncos -2

Baltimore Ravens vs. Jacksonville Jaguars

  • Pick: Jaguars +4

Cincinnati Bengals vs. Tennessee Titans

  • Pick: Bengals -1.5

Atlanta Falcons vs. Washington Commanders

  • Pick: Falcons +4.5

Los Angeles Chargers vs. Arizona Cardinals

  • Pick: Chargers -4.5

Las Vegas Raiders vs. Seattle Seahawks

  • Pick: Seahawks -3.5

New Orleans Saints vs. San Francisco 49ers

  • Pick: Saints +9.5

This line is an overreaction to the 49ers big win over the Cardinals on Monday Night Football. The Saints rank seventh in the NFL in net yards per play, and are much better than their record inidicates. I'll take the points with New Orleans.

Los Angeles Rams vs. Kansas City Chiefs

  • Pick: Chiefs -14.5

The Chiefs rank first in the NFL in yards per play and the Rams rank dead last. Not only that, but the Rams will be starting their third string quarterback, Bryce Perkins. It's going to get ugly in Kansas City.

Green Bay Packers vs. Philadelphia Eagles

  • Pick: Packers +7

Pittsburgh Steelers vs. Indianapolis Colts

  • Pick: Steelers +2.5

NFL Week 12 Betting Picks ATS for Every Game

You can track Iain's bets on Betstamp here.

Game odds refresh periodically and are subject to change.