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NFL Straight Up Picks for Every Team in Week 12

By Iain MacMillan

Tennessee Titans running back Derrick Henry (22) is stopped on fourth down on a tackle by Cincinnati
Tennessee Titans running back Derrick Henry (22) is stopped on fourth down on a tackle by Cincinnati / Kareem Elgazzar/The Enquirer / USA TODAY
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It's Thanksgiving week! That means all 32 teams will be in action for Week 12 and BYE weeks will resume next week.

With 16 games set to take place, I'll give you 16 picks. In this article, I'm going to focus on moneyline picks only. The point spread makes no difference here, we're only worried about what team is going to win the game.

Also, if you want my best bet for each game including spreads and totals, check out this week's episode of the Bacon Bets Podcast.

But for now, here are my straight up picks for all 16 NFL Week 12 games.

NFL Week 12 Moneyline Bets

Buffalo Bills vs. Detroit Lions

  • Pick: Bills -425

New York Giants vs. Dallas Cowboys

  • Pick: Cowboys -400

New England Patriots vs. Minnesota Vikings

  • Pick: Patriots +120

Chicago Bears vs. New York Jets

  • Pick: Jets -205

Mike White will be starting for the Jets on Sunday, but he may not be asked to do much as the Jets defense continues to be a top five unit in the NFL. They're rightfully favored in this spot.

Houston Texans vs. Miami Dolphins

Pick: Dolphins -625

Tampa Bay Buccaneers vs. Cleveland Browns

  • Pick: Browns +155

Denver Broncos vs. Carolina Panther

  • Pick: Broncos -130

Baltimore Ravens vs. Jacksonville Jaguars

  • Pick: Jaguars +172

This is my upset pick of the week. The offensive numbers between these two teams are nearly identical, but the Jaguars are built to stop the run on defense, which should give Ravens bettors cause for concern.

Cincinnati Bengals vs. Tennessee Titans

  • Pick: Bengals -126

Atlanta Falcons vs. Washington Commanders

  • Pick: Falcons +175

Los Angeles Chargers vs. Arizona Cardinals

  • Pick: Chargers -210

Las Vegas Raiders vs. Seattle Seahawks

  • Pick: Seahawks -180

The Seahawks are for real. Their 6-4 record is far from fraudulent as they've been one of the best statistical teams in the league this season. Their defense has been hot in recent weeks and the Raiders defense has been ice cold.

New Orleans Saints vs. San Francisco 49ers

  • Pick: 49ers -390

Los Angeles Rams vs. Kansas City Chiefs

  • Pick: Chiefs -1000

Green Bay Packers vs. Philadelphia Eagles

  • Pick: Packers +250

There has been holes exploited in the Eagles defense in recent weeks. They rank inside the bottom 10 in opponent yards per carry, struggling to stop the run. Now they face the Packers, who are inside the top 10 in yards per carry on offense. If Green Bay can run the ball successfully on Sunday night, they may be able to pull off the upset.

Pittsburgh Steelers vs. Indianapolis Colts

  • Pick: Steelers +122

You can track Iain's bets on Betstamp here.

Game odds refresh periodically and are subject to change.

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