NFL Week 1 Opening Odds: Buccaneers vs. Cowboys Kick-Off 2021 NFL Season on Thursday Night

The Tampa Bay Buccaneers will kick-off the 2021 NFL season against the Dallas Cowboys on Thursday night.
The Tampa Bay Buccaneers will kick-off the 2021 NFL season against the Dallas Cowboys on Thursday night. / Mark J. Rebilas-USA TODAY Sports
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Football season is officially here!

Now that we have Week 1 of the college football season in the books, it’s time to look ahead to the opening weekend of the National Football League.

The season kicks off on Thursday night when the defending Super Bowl champions, the Tampa Bay Buccaneers, take on the Dallas Cowboys in what promises to be a shootout. If you’re going to bet on the opening game (who isn’t?!) WynnBET is offering a special promotion to “triple the spread” for the game. Find out more details about the promotion here.

In usual NFL fashion, the majority of the games are set to take place on Sunday. The Chicago Bears and Los Angeles Rams will face-off in the first Sunday Night Football game of the season.

The league opted to not have a Monday night double-header like it had usually done in years past in Week 1, so a game between the Baltimore Ravens and Las Vegas Raiders will serve as the only matchup that night. It will serve as the finale for the opening weekend of the NFL season.

Here is the full slate of Week 1 NFL games. All odds listed are via WynnBET.

NFL Week 1 Odds - Thursday, Sept. 9th

Dallas Cowboys at Tampa Bay Buccaneers

Time: 8:30 p.m. EST

Channel: NBC

Line: Buccaneers -7.5

O/U: 51.5

NFL Week 1 Odds - Sunday, Sept. 12th

Jacksonville Jaguars at Houston Texans

Time: 1:00 p.m. EST

Channel: CBS

Line: Jaguars -3

O/U: 45

Los Angeles Chargers at Washington Football Team

Time: 1:00pm EST

Channel: CBS

Line: Chargers -1

Total: 44.5

Seattle Seahawks at Indianapolis Colts

Time: 1:00pm EST

Channel: FOX

Line: Seahawks -2.5

Total: 48.5

New York Jets at Carolina Panthers

Time: 1:00pm EST

Channel: CBS

Line: Panthers -5

Total: 45

Minnesota Vikings at Cincinnati Bengals

Time: 1:00pm EST

Channel: FOX

Line: Vikings -3

Total: 48

Arizona Cardinals at Tennessee Titans

Time: 1:00pm EST

Channel: CBS

Line: Titans -3

Total: 52

San Francisco 49ers at Detroit Lions

Time: 1:00pm EST

Channel: FOX

Line: 49ers -7.5

Total: 46

Pittsburgh Steelers at Buffalo Bills

Time: 1:00pm EST

Channel: CBS

Line: Bills -6.5

Total: 48.5

Philadelphia Eagles at Atlanta Falcons

Time: 1:00pm EST

Channel: FOX

Line: Falcons -3.5

Total: 48

Cleveland Browns at Kansas City Chiefs

Time: 4:25 pm EST

Channel: CBS

Line: Chiefs -6

Total: 53

Green Bay Packers vs New Orleans Saints*

*Location: Jacksonville, Florida

Time: 4:25pm EST

Channel: FOX

Line: Packers -4.5

Total: 50

Denver Broncos at New York Giants

Time: 4:25pm EST

Channel: FOX

Line: Broncos -2.5

Total: 42

Miami Dolphins at New England Patriots

Time: 4:25pm EST

Channel: CBS

Line: Patriots -2.5

Total: 44

Chicago Bears at Los Angeles Rams

Time: 8:20pm EST

Channel: NBC

Line: Rams -7.5

Total: 44.5

NFL Week 1 Odds - Monday, Sept. 13th

Time: 8:15pm EST

Channel: ESPN, ESPN 2

Line: Ravens -4.5

Total: 51


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