NFL Week 10 Schedule, Odds, Lines and Over/Unders (Every Team's Spread, Moneyline and Total)

Minnesota Vikings wide receiver Justin Jefferson (18) and quarterback Kirk Cousins (8) celebrate their touchdown vs. the Washington Commanders.
Minnesota Vikings wide receiver Justin Jefferson (18) and quarterback Kirk Cousins (8) celebrate their touchdown vs. the Washington Commanders. / Geoff Burke-USA TODAY Sports
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Most weeks, if someone mentioned that the Thursday Night primetime matchup was between a 4-5 Atlanta Falcons team and a 2-7 Carolina Panthers squad, even bettors might recognize that not every game they bet actually needs to be watched as well.

However, if it's anything half as good as what fans received back in Week 8 between these two teams, we may be in for the best Thursday Night Football game of the season!

Both teams traded blows in spectacular fashion a few weeks ago, highlighted with a spectacular comeback effort by Carolina on a hail mary connection from quarterback P.J. Walker to D.J Moore.

Unfortunately, the extra point was missed, and this NFC South battle went to overtime, with the Falcons eventually kicking the game-winner.

The Falcons are favorites on the road with a much lower total than the final result from the game a few weeks back.

Elsewhere in Week 10, the Buffalo Bills look to bounce back at home vs. the Minnesota Vikings in arguably the top matchup of the week from Orchard Park. Buffalo stunned the football world in Week 9; losing outright to the New York Jets on the road as a double digit underdog for their third loss of the season, and into a three-way tie in the AFC East with the aforementioned Jets and Miami Dolphins.

Meanwhile, despite the Vikings improving to 7-1 on the season following their road win in Washington, Kirk Cousins and crew are still more than a touchdown underdog in their second straight road matchup.

A total of 14 games go down this week in the NFL, including the first ever game in Munich, Germany as the Tampa Bay Buccaneers match up vs. the Seattle Seahawks as both teams come off big wins in Week 9.

Here are your opening odds for Week 10 in the NFL, along with the latest up-to-date lines currently available for every game on the board.

NFL Week 10 Odds for Every Team, Every Game


Game odds refresh periodically and are subject to change.