NFL Week 15 Upset Picks: Patriots, Bengals Included in Top Predictions

New England Patriots quarterback Mac Jones.
New England Patriots quarterback Mac Jones. / Mark Konezny-USA TODAY Sports
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The BetSided team had another positive week picking NFL upsets, going 2-1, and we're back with our favorite selections for the Week 15 slate.

At 29-21-1 on the season, there are a pair of AFC upsets with major playoff implications that our team likes this week.

Here’s who we are backing in this week’s slate, with odds via WynnBET Sportsbook:

New England Patriots (+120) at Indianapolis Colts

We’re at the point in the season where I don’t think I can doubt Bill Belichick any longer. 

His Patriots are a perfect 6-0 on the road this season and 5-1 against the spread heading into Week 15’s matchup with the Indianapolis Colts. I think Belichick is going to make Carson Wentz beat his team in this one and try to shut down Jonathan Taylor. 

On the other side, Bobby Okereke gave Mac Jones some bulletin board material by calling him out earlier this week. Despite that, Indy still allows 4.5 yards per carry this season which should make things easier on the Patriots running game. 

New England holds onto the AFC’s top spot with another win. – Peter Dewey


I’m shocked that the Colts are favored in this game. Why?

The Patriots’ defense is third in opponent yards per play, the Colts are 21st.

The Colts only path to victory in my opinion is for them to run the legs off Jonathan Taylor. The Colts’ weakness is their run defense, but if they have to throw the ball at all, do you trust Carson Wentz throwing the ball against the second best pass defense in the NFL, coached by the greatest coach in NFL history?

If there’s a way to confuse and exploit Carson Wentz, Bill Belichick will know it.

Finally, I know Mac Jones doesn’t toss the ball all over the field, but the Patriots are sneakily sixth in the NFL in yards per pass attempt. – Iain MacMillan

Cincinnati Bengals (+125) at Denver Broncos

The Bengals are only 7-6, but are one of the best 7-6 teams in the league. They are seventh in scoring, have the fourth-best rushing defense and are one of the most efficient passing offenses in the league. 

Cincinnati is being undervalued because of its recent losses. Yet, the Bengals are 2-1 this season straight up as road underdogs. Denver’s defense is credible, but its offense should allow the Bengals’ defense to make plays all day. I like the Bengals to get back into the playoff picture with a win. – Donnavan Smoot

Pittsburgh Steelers (+105) vs. Tennessee Titans

In Week 14, the Titans fresh off their bye hosted the Jaguars in Nashville and beat them handedly 20-0. But if you look closer into the box score, the Titans offense was far from dominant, averaging under 4 yards-per-play where they held the ball for nearly 37 minutes.

Meanwhile, the Steelers return home with extra rest after their comeback last Thursday night fell short, but they're playing hard and won't be intimidated by a Titans offense still figuring out their identity without Derrick Henry.

Mike Tomlin has also owned this spot in his career; going 35-13-1 against the spread as an underdog, and 13-3-2 ATS as a home dog. They'll be ready to pull off the upset and keep their slim playoff chances alive -- Ben Heisler


NFL Upset Picks to Date:

LAST WEEK: 2-1

SEASON RECORD: 29-21-1