Ohio State vs. Indiana Prediction, Odds, Spread and Over/Under for College Football Week 8

Ohio State has struggled to cover against Indiana in the past but the Hoosiers might be too bad to trust this year.
Ohio State has struggled to cover against Indiana in the past but the Hoosiers might be too bad to trust this year. / Joshua A. Bickel/Columbus Dispatch / USA

The Ohio State Buckeyes enter this seemingly easy game against Indiana well-rested and coming off a bye. For whatever reason, the Hoosier has proven problematic for the powerhouse team from Ohio. This is a road game for the Buckeyes as well. 

Luckily for Ohio State, the Hoosiers’ season has sputtered since starting the year ranked 17th. That didn’t last long after they opened the season with a loss to Iowa and three subsequent losses later, Ohio State is knocking on their door. Can IU win their first Big Ten conference game this year against the best the conference has to offer? 

Let’s check the odds from WynnBET Sportsbook and see if miracles really can happen. 

Ohio State vs. Indiana Odds, Spread, and Total


Ohio State: -18.0 (-110)

Indiana: +18.0 (-110)


Ohio State: -1000

Indiana: +650

Total: 60.5 (Over -110/Under -110)

Ohio State vs. Indiana Betting Trends

  • The OVER is 9-3 in Ohio State’s last 12 games.
  • Ohio State is 2-8 ATS in their last 10 games vs Indiana. 
  • Indiana is 1-6 ATS in their last 7 games. 
  • The UNDER is 5-0 in Indiana’s last 5 games vs the Big Ten. 

Ohio State vs. Indiana Prediction and Pick

The odds at WynnBET have Ohio State as 18 point favorites on Saturday night in Indiana. The line is quite reasonable all things considered and I thought it would be closer to 20. This could be due to the fact that Ohio State just can’t seem to find its footing when playing Indiana. Not to say that OSU is in any real danger of losing this game, but the Buckeyes have covered just twice in their last 10 games against the Hoosiers. 

Ohio State found it hard to cover against anyone earlier this season in fact. They opened the year with three straight ATS losses as double-digit favorites. OSU has been double-digit favorites in all six games this year. They managed to get back on track against Akron, winning by 52 points with a spread of 48.5 before going on to cover -15 against Rutgers and -22.0 against Maryland. 

Back from their bye week, OSU is a tempting fade ATS on the road vs Indiana. The thing is, the Hoosiers have been a mess this season both straight up and ATS. The team is 2-4 and has covered just one game all season. That game was as 31.5 point favorites over Idaho. Meanwhile, in games they are underdogs, they have failed to cover by almost 50 points combined. They lost by 28 as a 3.5 point underdog to Iowa and by 24 as 12.0 point dogs at Penn State. 

These recent results have me wary of trusting Indiana’s historic success at covering against Ohio state. I think that the Buckeyes, having an extra week to prepare for this game, will use Indiana as a jumping-off point for a dominant second half of the season. 

Prediction: Ohio State Buckeyes -18.0 (-110)

Exclusive offer. Bet $1, Win $100 if either team scores. PROMO CODE: BETSIDED. dark