Orioles vs. Yankees Prediction and Odds for Monday, May 23 (New York's Offense Set to Dominate Again)

May 22, 2022; Bronx, New York, USA;  New York Yankees designated hitter Aaron Judge (99) is greeted
May 22, 2022; Bronx, New York, USA; New York Yankees designated hitter Aaron Judge (99) is greeted / Wendell Cruz-USA TODAY Sports

Can anyone slow down the Yankees' offense?

Aaron Judge, Giancarlo Stanton, and Anthony Rizzo all rank in the top 10 in home runs so far in 2022, and begin another series at Yankee Stadium tonight where they've gone 15-6 this season.

New York reignites their season series with their AL East foe, the Baltimore Orioles Monday night with the MLB best record, 29-12 through 41 games. Ace Gerrit Cole takes the mound, opposed by Orioles' right-hander Jordan Lyles.

With one of the biggest moneylines of the season listed for this matchup, where is the betting value?

Here are the odds from WynnBET Sportsbook:

Orioles vs. Yankees Odds, Run Line, Total

Run Line:

  • Orioles: +1.5 (+125)
  • Yankees: -1.5 (-150)


  • Orioles: +260
  • Yankees: -320

Total: 7.5 (Over -120/Under +100)

Orioles vs. Yankees Prediction and Pick

It's not a matter of if, it's a matter of when the Yankees are going to plate runs against this Orioles pitching staff. The Bronx Bombers have lived up to their name with the third most home runs in baseball, 57 on the year, but there are levels to this offense, posting the best wRC+ in all of baseball. Weight Runs Created + is a normalized rate of run scoring chances across ball parks, meaning that the Yankees are constantly threatening to put runs on the board.

They should be able to knock around Jordan Lyles, who is pitching better in his first season with the O's, but still struggles with walks and hard contact. In a hitter-friendly Yankee Stadium, I believe the MLB's best team can help push this game over the total.

Cole will make his second straight start for the Yankees against Baltimore, pitching seven innings of two-run baseball against them last week. Even two runs will be a huge addition to this low total, but Cole is not as trustworthy as one would think, posting a FIP (Fielding Independent Pitching) north of 3.00.

With a hitter friendly park, and the best offense I like this total below eight runs.

LEAN: OVER 7.5 (-120)

You can find all of Reed's bets