Padres vs. Reds Prediction and Odds for Tuesday, April 26 (Cincinnati Looking for First Back-to-Back Wins of 2022)

Atlanta Braves v San Diego Padres
Atlanta Braves v San Diego Padres / Matt Thomas/San Diego Padres/GettyImages

It finally happened. After losing 11 straight games SU and ATS, the Reds finally broke that awful streak. Sadly, they also broke a streak of winning bets against them. But, let’s be clear. This team is still the same 3-13 group that has the worst record in the MLB. 

The Reds will kick off three-game series against the San Diego Padres on Tuesday at the Great American Ballpark in the hopes of winning their first back-to-back games all year.

I can’t say that I don’t have my doubts. The Padres completed a sweep of the Reds less than a week ago. It was a brutal beatdown as San Diego combined to win those three games 16-3 including a Game 3 shutout. The Padres are coming off a rough three games series where they lost 1-2 to the Los Angeles Dodgers. Nothing like going from playing the best team in the MLB to the worst. 

Here are the odds for this game, courtesy of WynnBET Sportsbook

Padres vs. Reds Odds, Run Line, and Total

Run Line

  • Padres: -1.5 (+100)
  • Reds: +1.5 (-120)


  • Padres: -165
  • Reds: +152


  • Total 8 (Over -110/Under -110)

Padres vs. Reds Prediction and Pick

As I said above, the Reds’ annoying win over the Cardinals did nothing to dissuade me from continuing my auto-fade of the Reds moving forward. This team still is just 1-11 in their last 12 games. It would be silly to assume that things are going to get better in a hurry. 

Reiver Sanmartin will get the start for Cincinnati as they look for a second win in a row. Unfortunately, Sanmartin has been pretty bad this year and I don’t think I can be trusted here. He last pitched against the Padres and coughed up five earned runs in 5 ⅓ innings of work. The loss dropped him to 0-2 with an ERA of 7.11. For reference, the Reds also have a poor bullpen ERA of 4.10. 

I am far more inclined to put my faith, and my money, on Joe Muscgove and the Padres tonight. Musgrove is coming off a solid outing against the Reds after going 6 ⅓ innings of two-run ball. He struck out seven and walked two in the winning effort. Musgrove is now 2-0 with a 1.89 ERA and squeaky clean 0.74 WHIP. 

I’m hopping right back on the Cincy fade train in this rematch of last week. 

Pick: Padres RL (+100)

Follow all of Matt De Saro’s betting picks HERE