Padres vs. Reds Prediction and Odds for Wednesday, April 27 (Bet on Musgrove to Dominate the Reds)

Cincinnati Reds v San Diego Padres
Cincinnati Reds v San Diego Padres / Matt Thomas/San Diego Padres/GettyImages

This Wednesday the San Diego Padres and Cincinnati Reds are back on the field for Game 2 of their three-game series at the Great American Ball Park. The Reds entered this series with the worst record in the MLB at just 3-13. While they did manage to break an 11-game losing streak their last time out against the Cardinals. The fact is that there was an 11-game losing streak to break in the first place. This team is awful, and they aren’t getting better anytime soon. 

The Padres know this and have already swept the Reds once this year in a three-game series. They owned the Reds, outscoring them 16-3 in that series. The Reds have scored more than two runs just once in their last nine games and shouldn't put up much of a fight against the 10-7 Padres. 

Here are the odds for this game, courtesy of WynnBET Sportsbook.

Padres vs. Reds Odds, Run Line, and Total

Run Line

  • Padres: -1.5 (-105)
  • Reds: +1.5 (-115)


  • Padres: -177
  • Reds: +162


  • Total 8.5 (Over -110/Under -110)

Padres vs. Reds Prediction and Pick

The Reds' offense is so bad that they will need a lights-out performance from their starting pitcher today. However, with a 5.54 ERA and 1.69 WHIP, Vladimir Guiterrez is anything but reliable. His last start was against the Padres and he lasted just 4 ⅔ innings after giving up three earned runs and walking four. It was the second game in a row that he failed to strike out more batters than he walked. 

If Guiterrez struggles, which I expect, the Reds do not have the firepower to keep them in this game. Cincy has the second-worst batting average in the MLB at .186, has just nine home runs in 527 at-bats, and is 25th in drawing walks. I don’t expect Guiterrez to last long which is a problem considering the Reds have a 4.10 bullpen ERA. 

Oh, and let's not forget that the Padres are starting Joe Musgrove here. He is 2-0 with a 1.89 ERA and 0.74 WHIP. I don't think I need to expand on that. Let the stats speak for themselves.

As has been the case in every game the Reds have played this year, all signs point to a loss. 

Pick: Padres -1.5 (-105)

Follow all of Matt De Saro’s betting picks HERE