Patriots vs. Cardinals Prediction and Odds for NFL Week 14 (Cardinals Have Value As Home Underdogs)

Nov 27, 2022; Glendale, AZ, USA; Arizona Cardinals wide receiver DeAndre Hopkins (10) celebrates
Nov 27, 2022; Glendale, AZ, USA; Arizona Cardinals wide receiver DeAndre Hopkins (10) celebrates / Michael Chow-USA TODAY Sports
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The New England Patriots travel to face the Arizona Cardinals to try and bounce back from their loss to the Buffalo Bills.

New England has lost two in a row and are currently outside of the playoffs. With five games left and one of the hardest remaining schedules, the Patriots need to get wins against the “lesser” teams in the league. 

Arizona is also on a two game losing streak and will likely miss the playoffs. However, can it play spoiler and make the Patriots’ road to the postseason tougher?

Let’s check out the odds. 

Patriots vs. Cardinals Spread, Odds and Over/Under

Patriots vs. Cardinals Betting Trends

  • Arizona is 2-3 ATS in its last five games
  • New England is 0-3 ATS in its last three games
  • The UNDER is 4-1 in the last five Patriots games
  • The OVER is 5-0-1 in the last six Cardinals games

Patriots vs. Cardinals Prediction and Pick

The Cardinals have struggled this season and are currently on a two-game losing streak. However, they have been good at bouncing back when it comes to covering. Arizona is 5-2 ATS following a loss this season. With a short spread and home-field advantage, you can keep the points because we’re going for the outright win. 

Over the last three weeks, New England’s offense has been based on the big play. Against the Jets and Bills, the Patriots’ lone touchdowns were by singular plays – getting the team to 10 points on the day. 

While the Cardinals defense isn’t as good as the Jets or Bills, the Patriots have shown multiple times they struggle to consistently move the ball up and down the field.

New England will also have to try and stop Deandre Hopkins and Hollywood Brown, and I don’t think they’ll succeed. 

I’ll take the short underdog to close out Week 14. 

You can find Donnavan Smoot’s full betting record here.


Game odds refresh periodically and are subject to change.