Rams vs. Cardinals Prediction, Odds, Against Spread and Over/Under for NFL Week 14

The Cardinals and the Rams will face-off for the second time this NFL season.
The Cardinals and the Rams will face-off for the second time this NFL season. / Gary A. Vasquez-USA TODAY Sports

A pivotal game in the NFC West is set to take place on Monday Night Football in Week 14 of the NFL season when the Arizona Cardinals host the Los Angeles Rams.

At 10-2, the Cardinals hold a two-game lead over their divisional opponent, but the Rams can cut that to one with a win on Sunday.

Los Angeles got back on track in Week 13, downing the Jaguars 37-7 after losing their three games prior. Arizona also secured a win last week, downing the Bears 33-22 in Chicago.

Let's take a look at the odds for the Week 14 edition of Monday Night Football courtesy of WynnBET.

Rams vs. Cardinals Odds, Spread, and Total


  • Rams +3 (-115)
  • Cardinals -3 (-105)


  • Rams +135
  • Cardinals -155


  • 52 (Over -110/Under -110)

Rams vs. Cardinals Betting Trends

  • Rams are 1-5 ATS in their last six games.
  • Rams are 7-1-1 ATS in their last nine meetings with the Cardinals.
  • Rams are 2-5 ATS in their last seven road games.
  • Cardinals are 8-2 ATS in their last 10 games.
  • Cardinals have the best straight up record in the NFL at 10-2.

Bet $1, Win $100 if either team scores a TD. . dark. Exclusive offer

Rams vs. Cardinals Prediction and Pick

The Rams hit a slump in their season, losing three straight ugly games, but I'm going to die on the hill of thinking Los Angeles is a serious Super Bowl contender.

The Rams rank first in the entire NFL in yards per play at 6.2, and their defense ranks fourth in the NFL in opponent yards per play at 5.1. The Cardinals rank 11th (5.7), and sixth (5.2) in those categories, but in their defense, they were without quarterback Kyler Murray for three games this season.

One key thing to note about the Arizona defense, is that it's vulnerable in the run game. It ranks 30th in the league in opponent yards per carry, allowing opposing teams to gain an average of 4.7 yards per rush. You may want to target Darrell Henderson or Sony Michel in fantasy this week.

The run game is a strength for the Rams, who rank second in opponent yards per carry keeping them to 3.8 yards per rush.

I'm going to back the statistics in this one, and continue to bet on the Rams.

Pick: Rams +3