Rams vs. Cardinals Prediction, Odds, Spread and Over/Under for NFL Week 3

Jan 17, 2022; Inglewood, California, USA; Los Angeles Rams quarterback Matthew Stafford (9) throws
Jan 17, 2022; Inglewood, California, USA; Los Angeles Rams quarterback Matthew Stafford (9) throws / Gary A. Vasquez-USA TODAY Sports

Two NFC West teams who are both sitting at 1-1, will meet in Week 3 when the Los Angeles Rams head to Glendale to take on the Arizona Cardinals.

The Cardinals are coming off a huge come-from-behind win, after being down by 16 points heading into the 4th quarter. Meanwhile, the Rams secured the win over the Falcons, but they almost ended up on the wrong side of a comeback, but a late Jalen Ramey interception secured them the victory.

Let's take a look at the odds for this NFC West showdown, courtesy of FanDuel Sportsbook.

Rams vs. Cardinals Odds, Spread, and Total

Rams vs. Cardinals Betting Trends

  • Rams are 9-1-1 ATS in their last 11 games vs. Cardinals.
  • Rams are 10-1 straight up in last 11 games vs. Cardinals.
  • Rams are 1-4 ATS in their last five games.
  • Cardinals are 2-6 ATS in their last eight games.
  • Cardinals are 0-6 ATS in their last six home games.
  • The OVER is 4-2 in the last six meetings between these teams.

Rams vs. Cardinals Prediction and Pick

Despite the big come-from-behind win over the Raiders in Week 2, there's still plenty of red flag surrounding this Arizona Cardinals team. For example, their defense is allowing 6.4 yards per play, and 7.7 yards per pass attempt.

Now they have to face one of the best passing attacks in the NFL in the Rams, and I expect to see a result similar to what we saw in Week 1 when they faced the Chiefs.

The Rams certainly haven't played to their potential yet either, but one area that's promising is their third down offense. They have converted on 52.17% of their third down attempts, which ranks fifth in the NFL. Meanwhile, the Cardinals are dead last in that stat, converting only 24% of their third down attempts.

Let's not forget who the Super Bowl champions are. It's Rams or nothing for me on Sunday.

You can track Iain's bets on Betstamp here.