Royals vs. White Sox Prediction and Odds for Tuesday, April 26 (Expect Runs in Chicago)

Apr 23, 2022; Minneapolis, Minnesota, USA;  Chicago White Sox first base Jose Abreu (79) celebrates
Apr 23, 2022; Minneapolis, Minnesota, USA; Chicago White Sox first base Jose Abreu (79) celebrates / Nick Wosika-USA TODAY Sports

Two AL Central foes get set for battle on Tuesday night.

The reigning division champions Chicago White Sox are off to a slow start as injuries have hindred them already this season, with Eloy Jimenez going down this weekend to a hamstring injury. Still, the team has one of the most vaunted lineups in baseball that mashes against left handed pitching, which they are set to face on Tuesday.

On the other signing it's been a concerning start for White Sox starter Dallas Keuchel this season as he is set to face a young and struggling Royals offense.

How do all of these factors play into the series opener on Tuesday? Let's check out the odds from WynnBET Sportsbook:

Royals vs. White Sox Odds, Run Line, Total

Run Line:

  • Royals: +1.5 (-150)
  • White Sox: -1.5 (+125)


  • Royals: +135
  • White Sox: -145

Total: 9 (Over -105/Under -115)

Royals vs. White Sox Prediction and Pick

Kansas City's offense has been weak to start the year, hitting .215 this season, and that number drops to .207 against left-handed pitching this season. Keuchel, a lefty, though has struggled to start the season. His ERA is 15.00 to start 2022 after allowing 10 runs in the first inning in his last appearance.

This comes on the heels of a 5.28 ERA from Keuchel in 2021, so the downward trend is continuing into this season and the Royals offense may be able to get on track against southpaw considering Keuhcel's concerning form.

However, the White Sox offense should have little issue against Royals starter Daniel Lynch. The fellow lefty has a 5.65 ERA in 17 starts across his first two seasons in the bigs. Now, he faces the White Sox, who have the second highest batting average against lefties (.290) and slugging percentage (.505).

I'm not interested in backing the White Sox as a favorite with Keuchel on the mound but I do like the over. Chicago should have little issue getting to Lynch and can get near this total themselves.


You can find all of Reed's bets HERE