South Carolina vs. Kentucky Prediction, Odds, Spread and Over/Under for College Football Week 6

Sep 3, 2022; Columbia, South Carolina, USA; South Carolina Gamecocks quarterback Spencer Rattler (7)
Sep 3, 2022; Columbia, South Carolina, USA; South Carolina Gamecocks quarterback Spencer Rattler (7) / Jeff Blake-USA TODAY Sports
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Can South Carolina get on track this season with Spencer Rattler under center, or will they fold to the elite competition of the SEC?

The Gamecocks travel to Lexington to face Kentucky on Saturday, who is coming off their first loss of the season last week at Ole Miss in a thriller. The Wildcats are still ranked while South Carolina is hoping to get some momentum during the midst of SEC play, but are catching double digits in this one.

Here are the odds and our best bet for Saturday's matchup:

Kentucky vs. South Carolina Odds, Spread and Total

Kentucky vs. South Carolina Betting Trends

  • Kentucky is 4-1 against the spread (ATS) this season
  • South Carolina is 0-2 ATS this season as an underdog
  • South Carolina has gone 3-2 to the OVER this season
  • Kentucky is 1-4 to the OVER this season

Kentucky vs. South Carolina Prediction and Pick

I broke this down as my favorite SEC bet on this week's Early Reed which you can watch below:

South Carolina's defense should be a pleasant surprise for this Kentucky team that just got back their running back, Chris Rodriguez, who was suspended for the first four games of the season, and now gets to feast on a South Carolina defense that is 113th in EPA/Rush. The Wildcats struggled to score against a near elite Ole Miss defense last week, losing 22-19 on the road, but also had two key fumbles in Rebels territory that cost them some points.

I think Kentucky's offense may breakout against South Carolina's porous defense, but Spencer Rattler's ability to push the ball down the field for the Gamecocks offense that is top 35 in explosive pass rate should show as well. The big issue for South Carolina is their ability to protect Rattler (74th in sacks allowed and 109th in tackles for loss allowed), but that won't factor in as much against a Wildcats defense that has six sacks in five games.

I think this total is being depressed due to Kentucky's low scoring SEC games against Florida (42 total points) and Ole Miss (41), but I think we clear 50 with ease due to the likely game script and Rattler's propensity for big plays, both good and bad.