Tennessee vs. LSU Prediction, Odds, Spread and Over/Under for College Football Week 6

Tennessee quarterback Hendon Hooker (5) looks to pass during Tennessee  s football game against
Tennessee quarterback Hendon Hooker (5) looks to pass during Tennessee s football game against / Calvin Mattheis/News Sentinel / USA
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One of the biggest matchups on Saturday's slate kicks off in the early window of Saturday's Week 6 slate.

Tennessee is off a bye week as a top 10 team set to face an LSU team that has won four straight games after losing in Week 1 to Florida State. With Alabama on deck, will the Volunteers get caught looking ahead to next week, or will they take care of business as a small road favorite.

Here are the odds from FanDuel Sportsbook:

Tennessee vs. LSU Odds, Spread and Total

Tennessee vs. LSU Betting Trends

  • Tennessee is 3-1 against the spread (ATS) this season
  • LSU covered in its only game as an underdog this season
  • LSU has gone UNDER in four of five games this season
  • Tennessee has gone OVER in three of four games

Tennessee vs. LSU Prediction and Pick

With the line inside of -3, this has to be a play on the Vols against a suspect LSU offense. For starters, Jayden Daniels is banged up after leaving the Auburn game early and the best source of Tigers offense has been broken play runs from the Arizona State quarterback.

If Daniels is in, I don't expect the Tigers offense to keep up with the elite Tennessee offense. LSU is 88th in EPA/Play when passing this season and the Tennessee defense is 21st overall in EPA/Play on the defensive side of the ball.

LSU was lucky to escape Auburn with a victory last week, 21-17, despite being outgained by more than 150 yards, and the Tennessee offense should maintain their elite form on Saturday. Hendon Hooker is in the center of the Heisman Trophy race (1,300 all-purpose yards, 11 total touchdowns) on one of the best offenses in the country that is averaging more than seven yards per play and fifth in success rate.

I'm still not sold on LSU just yet, who closed as a home underdog to Mississippi State a few weeks back, while Tennessee has gone on the road and beat Pitt already this season. I'll trust the better offense to outpace Brian Kelly's group on Saturday.

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Game odds refresh periodically and are subject to change.