Texans vs. Cardinals Prediction, Odds, Spread and Over/Under for NFL Week 7

Oct 17, 2021; Cleveland, Ohio, USA; Arizona Cardinals quarterback Kyler Murray (1) throws the ball
Oct 17, 2021; Cleveland, Ohio, USA; Arizona Cardinals quarterback Kyler Murray (1) throws the ball / Scott Galvin-USA TODAY Sports

The 1-5 Houston Texans will desperately try to put the brakes on their five-game losing streak on the road in Arizona this week. Problem is, Arizona is home to the 6-0 Cardinals who are looking to continue their unbeaten season en route to a playoff berth. 

The Texans were last rocked by the Colts and have totaled just 55 points during their 5-game losing streak. That works out to just a shade over 10 points per game on average and will not be nearly enough to hang with Arizona. 

The Cardinals, meanwhile, beat up on the Browns on the road 37-14 as Cleveland now has two of their top two running backs out. Kyler Murray continues to excel, throwing for four touchdowns last week. The defense also stepped up and forced three turnovers in what would prove to be Cleveland’s downfall. 

Despite their rough season, the Texans might be good value with such a large spread. With that in mind, let’s go over the odds from WynnBET Sportsbook and pick to see just how best to profit from this potential blowout. 

Texans vs. Cardinals Odds, Spread, and Total


  • Texans: +17.0 (-110)
  • Cardinals: -17.0 (-110)


  • Texans: +900
  • Cardinals: -1600

Total: 48.0 (Over -110/Under -110)

Texans vs. Cardinals Betting Trends

  • The Texans are on a 5-game SU losing streak and have lost 5 straight on the road.
  • The OVER is 6-2 in the last 8 games for the Cardinals at home.
  • The Cardinals are 5-1 ATS in their last 6 and 6-0 SU. 

Texans vs. Cardinals Prediction and Pick

The 17-point spread in this game makes things a bit tricky. There is no question in my mind that the Texans are a far inferior team and will lose this outright. But, will they get blown up by 17 or more against the Cardinals? 

Looking back at the Cardinals’ ATS results through the first six weeks we see some weird lines in my opinion. Maybe it is because I already know that the Cardinals won those games, but I don’t see why the Browns or the Rams were favored against this team. They covered those spreads by a combined 46.5 points so it seems the oddsmakers dropped the ball a bit on those games. 

But now, it feels like they have swung in the total opposite direction for this by putting the spread so high. At no point, this season has the Cardinals been more than an eight-point favorite and that was against the Jaguars. They ended up winning that game by 12, but, am I to believe that the Jaguars are that much better of a team than the Texans? Record aside, I am not sure there is a team worse than the Jags this year including the Lions or Texans. So what gives? 

I realize that the Texans will be forced to start one of their backup quarterbacks but, even still, 17 points is just too big a pill for me to swallow. There I will be betting on the Texans as much as it pains me to say.

Prediction: Texans +17.0 (-110)

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