Top MLB Picks and Predictions Today (Phillies, Astros are Delightful Dogs on Wednesday)

Philadelphia Phillies starting pitcher Zack Wheeler is a surprising underdog on the road vs. the struggling Toronto Blue Jays; losers of 9 of 11 games
Philadelphia Phillies starting pitcher Zack Wheeler is a surprising underdog on the road vs. the struggling Toronto Blue Jays; losers of 9 of 11 games / Tim Heitman/GettyImages

A handful of games are already underway this Wednesday in Major League Baseball, but as 10 games take place this evening, several questions remain for bettors?

Can the Pittsburgh Pirates win their fourth straight game as a moneyline underdog? Will the Mariners and Orioles each win 10 consecutive games in a row on the same day? Can Shohei Ohtani deliver as a favorite for the sinking Angels at home against the Astros?

Our team of writers and editors over at BetSided put together our favorite bets of the night in the Majors, as well as previews, picks and predictions for every game on the slate.

All odds are courtesy of WynnBET Sportsbook.

Phillies vs. Blue Jays Odds, Prediction and Pick

Run Line:

  • Phillies -1.5 (+155) | Blue Jays +1.5 (-190)


  • Phillies +105 | Blue Jays -115


  • 8 (OVER -105 | UNDER -115)

How on Earth is Zack Wheeler an underdog to Ross Stripling and a Blue Jays team that's 2-9 in its last 11?

Toronto just fired its manager and is scuffling.. Stripling has impressed but ranks in the 12th percentile in expected batting average while the Blue Jays lost both of his last two starts.

Meanwhile, Wheeler hasn't allowed a run in 17 straight innings and is deserving of Cy Young recognition. Coming off an All-Star snub, he should be furious and focused to mow down the Toronto lineup.

Philadelphia should improve to 5-2 in its last seven as a road underdog while the Blue Jays fall to 2-8 in their last 10 as a favorite.

PICK: Phillies +105

Follow all of Joe Summers' betting picks here.

Red Sox vs. Rays Odds, Prediction and Pick

Run Line:

  • Red Sox -1.5 (+105) | Rays +1.5 (-125)


  • Red Sox -152 | Rays +142


  • 7 (OVER -105 | UNDER -115)

This is easy. Shane McClanahan is on the mound, so I'll back him.

The left-hander is second in MLB in ERA, strikeouts and WHIP. He’s as dominant a pitcher as there is in the game, and the Rays are a smart bet to make when he’s pitching. 

Also, the Red Sox put John Winckowski on the mound. He hasn’t been awful this season, but he isn’t the ace McClanahan is. Winckowski’s ERA is over 4.00, he’s lost two straight starts and is coming off a bad performance against the Yankees.

I want to put my faith in McClanahan, so I’ll take the Rays’ first 5 innings run line. 

Lean: Rays F5 RL (-115) -- Donnavan Smoot

You can find Donnavan Smoot’s full betting record here.

Astros vs. Angels Odds, Prediction and Pick

Run Line:

  • Astros -1.5 (+105) | Angels +1.5 (-125)


  • Astros -152 | Angels +142


  • 7 (OVER +100 | UNDER -120)

Ohtani is the AL MVP. Yes, over Aaron Judge and don't "@" me. Still, I'm taking the superior team with a very good pitcher to prevail as a short road dog.

Ohtani's been awesome. He hasn't allowed an earned run in his last four, while only giving up one earned run over his last five starts in 33.2 innings.

Cristian Javier has also been terrific. The 25-year old for the Astros has a K/9 right up with Ohtani (12.33 to 12.29), while pitching to a 3.01 ERA and expected ERA (xERA) of 2.47; better than Ohtani (2.62).

I think the under is in play as well, but with the Angels' issues with their bullpen, I don't know if I fully trust them. It's also so low that any level of variance could throw it all away quickly.

Ultimately, two very similar pitchers are going head-to-head, but I'll back Houston's price tag as an underdog.

LEAN: Astros ML +109

Follow all of Ben's betting plays in real-time HERE