Who are the Biggest Favorites, Underdogs for College Football Week 2?

Bryce Young and Alabama are massive favorites in Week 2.
Bryce Young and Alabama are massive favorites in Week 2. / Jason Getz-USA TODAY Sports

Week 2 of the college football season is set to kick off, and our BetSided team has you covered. 

If you’re looking for best bets, upset picks or even identifying which lines could be a trap, they’re all available on our college football homepage. 

Prior to Week 2 kicking off, here is a look at some of the biggest favorites and underdogs in Saturday’s slate with all odds via WynnBET

Biggest Favorites and Underdogs in College Football Week 2 Odds

A few top-25 teams are heavy favorites in their Week 2 matchups, including the Auburn Tigers, Cincinnati Bearcats and top-ranked Alabama Crimson Tide. 

No. 25 Auburn vs. Alabama State Odds

Spread: Auburn -49.5 (-110)

Bo Nix and Auburn are looking to keep themselves in the top-25 for the remainder of the season.

Wake Forest vs. Norfolk State Odds

Spread: Wake Forest -43.0 (-110)

Wake Forest took its opener by 32 points, and it is favored to have a similar result in Week 2. 

Tulane vs. Morgan State Odds

Spread: Tulane -46.5 (-110) 

Tulane gave Oklahoma a run in Week 1, and it is expected to easily handle Morgan State this week.

No. 7 Cincinnati vs. Murray State Odds

Spread: Cincinnati -36.5 (-110)

The Bearcats are looking to benefit from some shaky play by some of the top College Football Playoff contenders in Week 1.

No. 1 Alabama vs. Mercer

Spread: Alabama -55.0 (-110)

The Crimson Tide and Bryce Young dismantled No. 22 Miami in their season opener, and they’ll look to roll over a much easier Mercer team in Week 2. 

West Virginia vs. Long Island Odds

Spread: West Virginia -48.5 (-110)

The Mountaineers are looking to get back on track after losing to Maryland in the season opener. 

No. 6 Clemson vs. South Carolina State Odds

Spread: Clemson -50.0 (-115)

Dabo Swinney’s team is looking to bounce back from its Week 1 loss to Georgia. 

No. 4 Oklahoma vs. Western Carolina Odds

Spread: Oklahoma -50.5 (-110)

Spencer Rattler and the Sooners need a bounce-back game after fending off Tulane in Week 1.

Think one of these favorites will cover the massive spread? Download the WynnBET app to make your pick.