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Who are the Biggest Favorites, Underdogs for Week 1 in College Football?

By Ben Heisler

Wake Forest could put up a ton of points in their Week 1 matchup vs. Old Dominion.
Wake Forest could put up a ton of points in their Week 1 matchup vs. Old Dominion. / Rich Barnes-USA TODAY Sports
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The Week 1 college football slate may be filled with plenty of compelling matchups and expected close games, but there are also some heavy favorites on the board as well.

When oddsmakers are hanging numbers of 30-plus points or more, it's not only an indication that the favorite should win easily, but they're also trying to get some even action on the other side of the matchup as well.

Based on the provided odds from WynnBET Sportsbook, here are the largest favorites on the board for this week with odds of 30 points or higher:

Biggest College Football Favorites: Friday, September 3rd

Old Dominion vs. Wake Forest (-32.0) | Total: 61.5

St. Francis (PA) vs. Eastern Michigan (-32.5) | Total: 54.5

Northern Colorado vs. Colorado (-38.0) | Total: 56.5

Wake Forest, along with Oklahoma and Texas A&M were at one point, amongst the top 3 this week at WynnBET for the highest scoring team in Week 1. The Demon Deacons are projected to score 46.5 total points at home against the Monarchs, with the under 46.5 slightly juiced to -120 (bet $120 to win $100).

Eastern Michigan is expected to drop 43.5 points on St. Francis, while Colorado with the highest point spread of the night, is projected for 47 total points, juiced to -120 on the under as well.

Biggest College Football Favorites: Saturday, September 4th

No. 2 Oklahoma vs. Tulane (+31.5) | Total: 67.5

UL Monroe vs. Kentucky (-31.0) | Total: 54.0

Massachusetts vs. Pittsburgh (-38.0) | Total: 56.0

Akron vs. Auburn (-37.0) | Total: 55.5

New Mexico State vs. San Diego State (-31.5) | Total: 51.0

The No. 2 ranked Oklahoma Sooners and Heisman candidate Spencer Rattler are projected to score a whopping 49.5 points over Tulane. The Green Wave will now have to play their "home game" in Norman, Oklahoma after the after-effects from Hurricane Ida moved the matchup.

The Pittsburgh Panthers, tied with Colorado for the highest point spread of the week at 38, are projected for 47 points when they welcome the Minute Men at Heinz Field.

Like the point spread or over/under on any of these massive favorites and underdogs?

Get your Week 1 college football picks in and win at WynnBET Sportsbook, and get your first bet up to $1,000 risk free!

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