Wisconsin vs. Ohio State Prediction, Odds, Spread and Over/Under for College Football Week 4

Sep 17, 2022; Columbus, Ohio, USA; Ohio State Buckeyes quarterback C.J. Stroud (7) throws a pass
Sep 17, 2022; Columbus, Ohio, USA; Ohio State Buckeyes quarterback C.J. Stroud (7) throws a pass / Adam Cairns/Columbus Dispatch / USA

Big Ten play gets started for a pair of contenders in Columbus, Ohio.

Ohio State's offense has rounded into form, putting up 77 points against Toledo last week, and now turn their attention to Wisconsin, who is still trying to figure out their identity in the competitive Big Ten West.

Can the Buckeyes overwhelm the Badgers run first offense en route to a blowout victory? Let's check out the odds and find the best bet:

Wisconsin vs. Ohio State Odds, Spread and Total

Wisconsin vs. Ohio State Betting Trends

  • Ohio State is 14-9-1 against the spread (ATS) in Big Ten play under Ryan Day
  • Wisconsin is 1-1 ATS as an underdog of 14 or more under Paul Chryst (both at Ohio State)
  • Ohio State has gone under in 7 of 12 games with a total of 60 or below with Ryan Day as head coach

Wisconsin vs. Ohio State Prediction and Pick

Ohio State's offense is now humming, Jaxon Smith-Njigba returned from injury last week and I expect the wide receiver to continue seeing more targets, and this is a big issue for the Badgers.

Wisconsin wants to play physical, bully ball football on the ground with Braelon Allen, but that won't be the case with Ohio State likely scoring at will. The Badgers defense hasn't been challenged all that much to date, but they are weaker in the secondary than usual Wisconsin teams. They are outside the top 100 in explosive pass defense and that's going to be problematic against the Buckeyes, who are top 20 in that metric on offense.

If the Badgers fall behind early, I don't trust Graham Mertz to keep the team within shouting distance, so I'll look to back Ohio State at below -20. I'd also look to the team total over if you don't believe the Buckeyes defense can keep down Wisconsin's offense.

However, if you look to the Notre Dame Week 1 matchup, Ohio State shut down a ground-oriented Irish attack to 2.53 yards per carry. I expect more of the same here.