Wyoming vs. Indiana Prediction and Odds for NCAA Men's Tournament First Four

Wyoming and Indiana are each 12 seed's in the First Four in Dayton as part of the East region. The winner will face St. Mary's in the official first round of the NCAA Tournament.

Indiana's late surge in the Big Ten Tournament, making it to the semifinals was good enough to earn an at-large berth while Wyoming's strong play in the Mountain West Conference also secured them a No. 12 seed in the NCAA Tournament.

Here are the odds from WynnBET Sportsbook and statistical breakdown for each team as well as an early bet:

Wyoming vs. Indiana Odds, Spread and Total

Spread:

• Wyoming: +4 (-110)
• Indiana: -4 (-110)

Moneyline:

• Wyoming: N/A
• Indiana: N/A\

Total: 132 (Over -110/Under -110)

Wyoming vs. Indiana Analysis

Wyoming

Overall Record: 25-8

ATS Record:17-13-2

Over/Under Record: 18-15

SoS: 98th

Adjusted Offensive Efficiency: 110.2

Defensive Efficiency: 97.1

eFG%: 52.4%

FT%: 72.5%

3PT%: 33.0%

Last Year’s Tournament Result: N/A

Odds to win National Championship: +3000 (Field)

Indiana

Overall Record: 20-13

ATS Record:19-14

Over/Under Record: 16-17

SoS: 22nd

Adjusted Offensive Efficiency: 107.5

Defensive Efficiency: 92.6

eFG%: 51.3%

FT%: 69.9%

3PT%: 33.9%

Last Year’s Tournament Result: N/A

Odds to win National Championship: +3000 (Field)

Wyoming vs. Indiana Prediction and Pick

While Indiana is the hot team at the moment, I think they are in an unfavorable spot as a favorite now. The team was able to do damage in the Big Ten Tournament as underdogs, but now will be the hunted.

I like swiss army knife guard Hunter Maldanaldo, who is fantastic in post up situations and can give the Indiana back court fits, to operate down low and find shooters on the perimeter. Wyoming has shot makers on the outside in Brendan Wenzel and Xavier DuSell to hang in this game.

The Cowboys protect the ball well, 62nd in the country in turnover rate and have a reliable big man in Graham Ike that can match up with Trayce Jackson-Davis. Wyoming has played teams close all season while Indiana has struggled to close out games, I'll take the Mountain West dog at over two buckets.

PICK: Wyoming +4, play to +2.5

Follow BetSided's March Madness Hub throughout the entirety of the NCAA men's and women's tournaments for full betting previews and picks for every game, updated betting odds , futures for the Final Four and national championship, insights, trends, videos, podcasts and more!