49ers vs. Bengals Updated Odds and Prediction: What Bettors Need to Know

Nov 28, 2021; Santa Clara, California, USA;  San Francisco 49ers quarterback Jimmy Garoppolo (10)
Nov 28, 2021; Santa Clara, California, USA; San Francisco 49ers quarterback Jimmy Garoppolo (10) / Kelley L Cox-USA TODAY Sports
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The San Francisco 49ers travel to Cincinnati to face the Bengals in a battle of two playoff hopefuls.

The Bengals may have had some concerning injury news around their quarterback Joe Burrow, who dislocated his finger last week during the team's loss to the Chargers, but he's on track to play on Sunday.

There's been some mid-week line movement despite Burrow's promising health in this one so let's break down the updated odds from WynnBET Sportsbook.

49ers vs. Bengals Odds, Spread and Total

Spread:

  • 49ers: -1.5 (-110)
  • Bengals: +1.5 (-110)

Moneyline:

  • 49ers: -125
  • Bengals: +105

Total: 49 (Over -110/Under -110)

49ers vs Bengals Betting Trends

  • 49ers are 4-2 ATS in their last six games.
  • The OVER is 5-2 in the 49ers last seven games.
  • 49ers are 12-3 SU in their last 15 games vs. Bengals.
  • The OVER is 5-1 in the Bengals last six games.
  • The UNDER is 8-1 in the Bengals last nine games vs. NFC opponents.

49ers vs Bengals Prediction and Pick

While noting some areas of concerns against the Bengals, our Iain McMillian made the case for the Niners earlier in the week, who have moved to favorites at WynnBET.

"The 49ers have the advantage in a majority of categories. San Francisco ranks sixth in yards per play (6.0) and 10th in opponent yards per play (5.3), while the Bengals rank 13th (5.7) and 20th (5.6) in those stats respectively. ...If there's one area where the Bengals can exploit the 49ers, it's on the ground. They've averaged 4.5 yards per rush over their last three games, and now they face a 49ers team that is allowing 4.4 yards per carry this season, which ranks 20th in the NFL.

Despite that, I'm going to back what most statistics tell me, which is that the 49ers have been the better football team this season, regardless of record."

Pick: 49ers -110