Best Bets for NFL Week 15 (Two Road Favorites Highlight Top Predictions)

Best NFL bets for Week 15 of the 2023 season!

Atlanta Falcons running back Bijan Robinson.
Atlanta Falcons running back Bijan Robinson. / Dale Zanine-USA TODAY Sports
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Week 14 was a perfect showing from the BetSided team in their best bets, with the San Francisco 49ers and Dallas Cowboys both covering the number as favorites.

Over the last eight weeks, Iain MacMillan and Peter Dewey have gone a combined 12-3-1 in these picks, and we have two more bets -- both on favorites -- to place in Week 15.

For more Week 15 picks, check out our NFL betting analyst Iain MacMillan’s best bet for every game on the slate here!

With just four weeks left in the NFL regular season, there are some teams that we won't get to bet on -- or fade -- once the playoffs come. There are two struggling squads worth fading in this week's edition of NFL Best Bets.

If you're thinking of tailing these bets -- or even fading them -- FanDuel Sportsbook has an amazing promotional offer. New users who sign up with the link below and wager $5 will receive $150 in bonus bets (if your team wins). So, even if you don't want to take our spread picks, simply bet on a winner to take advantage of this offer!

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NFL Week 15 Best Bets

San Francisco 49ers -12.5 vs. Arizona Cardinals

This is a road game, but I'm still not worried about laying the points with San Francisco this week.

The 49ers were able to cover my best bet last week, and they've won every game since their bye week by 12 or more points. That includes blowout wins over the Philadelphia Eagles and Jacksonville Jaguars.

Now, they get a matchup with an Arizona team that has allowed the third-most points in the NFL so far this season.

When the 49ers' offense is healthy (all the stars in action) they are now 22-0 (!) straight up with a +375 point differential.

Don't let the number scare you away from betting on the best team in the NFL this week. -- Peter Dewey

Atlanta Falcons -3 vs. Carolina Panthers

Let's just start with the obvious, the Atlanta Falcons are the better team.

Atlanta enters the game ranking 12th in Net Yards per Play this season at +0.1 and seventh in Net Yards per Play over their last three games (+0.4). The Carolina Panthers are 31st for season-long numbers at -1 and 28th over their last three games at -1.

It's clear the Falcons are, at the very least, much better at moving the ball down the field and preventing their opponents from doing so.

Then we can talk about the stylistic advantage the Falcons have. They've run the ball on 48.02% of plays this season and 51.79% of plays over their last three games. Now, they get to face the worst run defense in the NFL. The Panthers are dead last in both opponent rush EPA and opponent rush success rate.

The Falcons will be able to run the ball all game and should have no issue shutting down the Panthers' decrepit offense which has scored just 15.2 points per game this season.

I'll lay the field goal with the Dirty Birds. -- Iain MacMillan


Game odds refresh periodically and are subject to change.

Find Peter Dewey's betting record here.

You can check out all of Iain's bets here!