Best Prop Bets for Chargers vs. Cardinals in Week 12 (Fade Cardinals Secondary, Chargers Rush Defense)

The Chargers and Cardinals meet in Arizona in a battle of west coast teams with Kyler Murray set to return from a hamstring injury that has cost him the last two games.

While you can check out our full game preview here, this article is going to focus on three prop bets to attack in this afternoon matchup between two teams that have exploitable defenses. The total is only 48.5, but this could be underrating what could become a shootout in the desert.

Here are three prop bets to make for this one:

Best NFL Prop Bets for Chargers vs. Cardinals

• Justin Herbert OVER 281.5 Passing Yards
• Austin Ekeler OVER 38.5 Passing Yards
• James Conner OVER 63.5 Rushing Yards

Justin Herbert OVER 281.5 Passing Yards

The Cardinals secondary has struggled all season 20th in EPA/Pass and 32nd in success rate. This is going to be problematic against a Chargers offense that focuses on the pass game. Herbert is second in pass attempts this season and sixth in passing yards.

With Keenan Allen finally healthy the Chargers passing game is as scary as ever and should have little issue clearing this total and getting to 300 yards, which he hasn't been able to since Week 4. However, with the favorable matchup, I'll buy low on Los Angeles' passing game to get going.

Austin Ekeler OVER 38.5 Passing Yards

Ekeler has 83 targets on the season, the most on the team, and I expect him to be the primary target for LA's passing game once again out of the backfield. With Arizona's inability to slow down the passing game I think we can expect an above average outing from Ekeler.

For reference, Ekeler has gone over this total in six of 10 games on the year.

James Conner OVER 63.5 Rushing Yards

The Chargers have one of the worst rush defenses in the league, 30th in EPA/Rush and 31st in success rate allowed on the ground. This is good news for a team getting their dual threat quarterback Kyler Murray back from injury, but I'm going to focus on Conner, who should be due for a breakout game now that the Cardinals offense is whole.

Conner is averaging only 44.5 yards per game, but the Chargers inability to slow down the ground game is going to be the point of attack for Arizona. I'm going to key in on the two games prior to Murray's injury as a key point for Conner, who was thriving before then. He averaged more than six yards per carry in games against the Seahawks and Eagles and I think we see similar output against Los Angeles.

Track all of Reed's bets at Betstamp HERE!

Game odds refresh periodically and are subject to change.