Betsided

Bills vs. Saints Updated Odds and Prediction (What Bettors Need to Know)

By Donnavan Smoot

Josh Allen and the Bills will have a tough time in New Orleans on Thanksgiving.
Josh Allen and the Bills will have a tough time in New Orleans on Thanksgiving. / Rich Barnes-USA TODAY Sports
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The Buffalo Bills are sputtering right now, going 1-2 in the last three games and losing the lead in the AFC East. They're hoping to get back on track against the struggling Saints. New Orleans hasn't been the same since Jameis Winston went down and they are trying to stay in the playoff hunt without him.

Thanksgiving night games are often the forgotten ones, but the playoff implications in this one are sure to make it a fun way to end the night.

Here are the odds for their matchup via WynnBET.

Bills vs. Saints Spread, Odds and Over/Under

Spread: 

  • Bills: -6.0 (-110)
  • Saints: +6.0 (-110)

Moneyline: 

  • Bills: -260
  • Saints +220

Total: 45.5 (Over: -110/Under: -110)

Bills vs. Saints Betting Trends

  • The Saints are 10-5 ATS as home underdogs under Sean Payton.
  • The Bills are 7-5 ATS as road favorites with Josh Allen at quarterback.
  • New Orleans is 6-4 to the OVER this season.
  • Buffalo is 5-5 on the OVER/UNDER this season.

Bills vs. Saints Prediction and Pick

Earlier in the week, our own Reed Wallach made his pick for the Thanksgiving Night game. Here's what he had to say.

“While my number projects the Bills as a bigger favorite than this, I can't back them as a road favorite in this spot. With limited time to prepare, I'm likely going to end up betting the Saints on an initial pass, but I will need to see each team's injury report. New Orleans has been without Alvin Kamara for the past two weeks, and had several injuries on the offensive line heading into the Eagles game.”

“My favorite play is on to be on the under. The Saints defense remains is inside the top six in EPA/Play and the Bills should have no issue with a Trevor Siemian-led New Orleans offense. Buffalo is second in EPA/Play.”

“The Bills have quietly been an under team lately, going under the total in three of their last four, and on a short week I can see a low scoring affair once again.”

While I respect Wallach’s pick, I’m going to fade him on this one. The Saints are still rolling with Trevor Siemian and I can’t put my faith in him to beat a Bills defense that is still solid. The Saints will have homefield advantage and will make this game close.

Pick: Saints +6.0

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