Chargers vs. Texans Prediction, Odds, Spread and Over/Under for NFL Week 4

The injury bug has gotten to the Los Angeles Chargers in a big way early in the 2022 season, as the team has lost starting left tackle Rashawn Slater for the season as well as receiver Jalen Guyton. 

Justin Herbert, Joey Bosa and Keenan Allen are all also banged up entering a Week 4 tilt with the Houston Texans. 

The Texans squandered an opportunity for their first win of the 2022 season against the Chicago Bears in Week 3, but they still managed to push for bettors that had them at +3 in that matchup. 

Davis Mills is going to need to play much better if he wants Houston to consider him for the starting job beyond this season, but the team did seem to find some offense with rookie running back Dameon Pierce (20 carries, 80 yards and a touchdown) in Week 3. 

Can Lovie Smith’s squad pull off the upset against a banged-up Chargers team?

Here are the latest odds for this Week 4 showdown: 

Chargers vs. Texans Odds, Spread and Total

Texans vs. Chargers Betting Trends

• The Texans are 2-0-1 ATS this season
• The Chargers are 2-1 ATS this season
• The UNDER is 2-1 in both the Chargers and Texans three games this season
• The Chargers are 6-2 ATS in their last eight games against the Texans
• The Texans are 1-7-1 straight up in their last nine home games
• The Chargers are 0-3 ATS as road favorites under Brandon Staley

Chargers vs. Texans Prediction and Pick

This is a really interesting spot, as the Chargers have yet to cover as road favorites under head coach Brandon Staley. Granted, it has been just three games, but Los Angeles certainly needs a convincing win in Week 4 after getting blown out by the Jacksonville Jaguars in Week 3. 

The health of Herbert (ribs) is the key for the Chargers, as he did not look himself against Jacksonville. There’s a possibility that Allen will return to the lineup after missing the last two games, which would be a major boost to the Chargers offense. 

On the other side, I’m not sure I believe in Houston’s solid start against the spread this season. The Texans tied an Indianapolis Colts team that notoriously starts slow, and they actually blew a 20-3 lead to allow the game to end in a tie. 

Then, they failed to generate any offense against a struggling Denver Broncos team in Week 2 before losing to Justin Fields and the Bears, thanks to two picks by Mills. 

At BetMGM, you can get the Chargers at -4.5 right now, and that would be the way I’d lean in this game. Even with the injuries, Los Angeles is a superior team talent wise, and Herbert is the far better quarterback as long as he’s able to play. 

Find Peter Dewey’s full betting record here.