Monday Night Football Best Prop Bets For Rams vs. Cardinals

Arguably the game of the week takes place on Monday Night Football with the Arizona Cardinals playing host to the Los Angeles Rams in a game that may decide the NFC West.

The Cards are 2.5-point favorites at WynnBET Sportsbook, you can find our game preview here, but let's hit the prop market to find some valuable wagers.

Best Prop Bets for Rams vs. Cardinals

• DeAndre Hopkins OVER 59.5 Receiving Yards (-115)
• Cooper Kupp OVER 94.5 Receiving Yards (-115)
• Matthew Stafford UNDER 285.5 Passing Yards (-115)

DeAndre Hopkins OVER 59.5 Receiving Yards (-115)

Hopkins made his return to the lineup for the 10-2 Cardinals last week against the Bears, playing 74% of snaps and hauling in a beautiful 21-yard touchdown.

While Jalen Ramsey has had his number in the past, I think this line is too low for a player of Hopkins' stature and a game that should have points early and often with a total of 51.5.

Hopkins had four catches for 67 yards on seven targets against the Rams earlier in the year, and after easing back from the mid-season injury, I believe Kyler Murray and the offense key in on Hopkins often.

'Nuke' has gone over in four of nine games this season, I'll take my chances.

Cooper Kupp OVER 94.5 Receiving Yards (-115)

Anything under 100 yards is an auto play on Kupp, the Rams clear No. 1 target.

Kupp has cleared this total in more than half of his games this total in 10 of 13 games this season. It's worth noting that he went under this prop in the team's first matchup against the Cards, but did receive 13 targets.

This is a sky high total, but not for Kupp. I'm counting on him to get his usual quota and clear this number.

Matthew Stafford UNDER 285.5 Passing Yards (-115)

For starters, the Arizona pass defense is fantastic, eighth in success rate and second in explosive pass defense.

I believe that Sean McVay and the Rams will look to attack on the ground against a vulnerable Cards front seven that is the worst in the NFL in explosive rush defense.

There are also questions around the health of Stafford. While his numbers may look fine, Stafford has been battling several ailing issues which has limited his mobility.

There's also the question of trying to go shot for shot with the Cardinals offense and a fully healthy Murray. If Stafford isn't 100%, would the Rams try to control the clock and keep Arizona off the field with a ground-based attack?