NFL Week 2 Opening Odds: Mahomes-Jackson Showdown Highlights Sunday Slate

Mahomes and the Chiefs pulled off the comeback against the Browns to start 1-0.
Mahomes and the Chiefs pulled off the comeback against the Browns to start 1-0. / Jay Biggerstaff-USA TODAY Sports
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We made it. The first full Sunday of the NFL season is in the books and everything seems right again.

With all the upsets and surprise performances that came with Week 1, the only thing on our minds is what will Week 2 have in store for us.

WynnBET has released the opening odds for Week 2, and there are already some interesting matchups. The week starts with an NFC East battle on Thursday night between the Giants and Washington, while Sunday concludes with a Patrick Mahomes-Lamar Jackson showdown.

NFL Week 2 Odds - Thursday, Sept. 16th

New York Giants at Washington Football Team

Time: 8:20 p.m. EST

Channel: NFL Network

Line: Washington -4.5

O/U: 42.5

NFL Week 2 Odds - Sunday, Sept. 19th

Buffalo Bills at Miami Dolphins

Time: 1:00 p.m. EST

Channel: FOX

Line: Bills -3.5

O/U: 48.0

Denver Broncos at Jacksonville Jaguars

Time: 1:00pm EST

Channel: CBS

Line: Broncos -6

Total: 44.0

Houston Texans at Cleveland Browns

Time: 1:00pm EST

Channel: CBS

Line: Browns -11.5

Total: 48.0

New England Patriots at New York Jets

Time: 1:00pm EST

Channel: CBS

Line: Patriots -3.5

Total: 43.0

New Orleans Saints at Carolina Panthers

Time: 1:00pm EST

Channel: FOX

Line: Saints -3

Total: 46.0

San Francisco 49ers at Philadelphia Eagles

Time: 1:00pm EST

Channel: FOX

Line: 49ers -3

Total: 48.0

Cincinnati Bengals at Chicago Bears

Time: 1:00pm EST

Channel: FOX

Line: Bears -3.5

Total: 45.5

Las Vegas Raiders at Pittsburgh Steelers

Time: 1:00pm EST

Channel: CBS

Line: Steelers -6.5

Total: 48.5

Los Angeles Rams at Indianapolis Colts

Time: 1:00pm EST

Channel: FOX

Line: Rams -4

Total: 47.0

Minnesota Vikings at Arizona Cardinals

Time: 3:05 pm EST

Channel: FOX

Line: Cardinals -4

Total: 51.0

Dallas Cowboys at Los Angeles Chargers

Time: 4:25pm EST

Channel: CBS

Line: Chargers -3

Total: 52.0

Tennessee Titans at Seattle Seahawks

Time: 4:25pm EST

Channel: CBS

Line: Seahawks -6

Total: 52.5

Atlanta Falcons at Tampa Bay Buccaneers

Time: 4:25pm EST

Channel: FOX

Line: Buccaneers -12.5

Total: 52.5

Kansas City Chiefs at Baltimore Ravens

Time: 8:20pm EST

Channel: NBC

Line: Chiefs -3

Total: 55.5

NFL Week 2 Odds - Monday, Sept. 20th

Detroit Lions at Green Bay Packers

Time: 8:15pm EST

Channel: ESPN, ESPN 2

Line: Packers -11

Total: 49.5


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