Ohio State vs. Michigan Updated Odds and Prediction: What Bettors Need to Know

C.J. Stroud and the Buckeyes are heavy favorites on the road against Michigan.
C.J. Stroud and the Buckeyes are heavy favorites on the road against Michigan. / Adam Cairns/Columbus Dispatch / USA

Ohio State and Michigan will renew one of the greatest rivalries in sports tomorrow from Ann Arbor, MI. The Buckeyes are coming off a trouncing of the Michigan State Spartans, while the Wolverines are trying to get back into the Big 10 East driver's seat. Tomorrow will be one of the most important games of the college football season, and BetSided has you covered with the latest odds.

Here are the odds for their matchup via WynnBET.

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Ohio State vs. Michigan Updated Spread, Odds and Over/Under


  • Ohio State: -7.0 (-110)
  • Michigan: +7.0 (-110)


  • Ohio State: -310
  • Michigan: +255
  • Total: 64.5 (Over: -110/Under: -110)

Ohio State vs. Michigan Betting Trends

  • The Buckeyes are 6-2 against the spread (ATS) in their last eight games.
  • The Buckeyes are 9-0 straight up (SU) in their last nine games. 
  • The Buckeyes are 8-0 SU in their last eight games against the Wolverines. 
  • The OVER is 5-0 in the last five games between these two teams at the Big House. 
  • Ohio State is 5-2 ATS in their last seven games against Big Ten teams. 
  •  The Wolverines are 6-1 ATS in their last seven games. 
  • The Wolverines are 10-1 SU in their last 11 games. 
  • The OVER is 7-0 in the last seven games between these two teams. 

Ohio State vs. Michigan Prediction and Pick

Earlier this week, BetSided’s Matt De Saro made his pick on this game and chose to back the Wolverines in Ann Arbor. 

“Michigan is tied for the best ATS record in College Football with Oklahoma State at 9-2 and is on a three-game ATS win streak.” 

“I think that as much of a great story as it would be, the Wolverines fall yet again to their eternal rivals. However, unlike in many years past, I think they hang close and manage to cover.” 

I’m going to have to disagree with De Saro here. The Buckeyes are the most explosive team in the country and I don’t think Michigan will break its curse -- especially not against the trio of wide receivers Ohio State has. 

Pick: Ohio State -7.0 (-110)