Week 2 College Football Opening Odds: Oregon vs. Ohio State, Iowa State vs. Iowa Highlight Slate

C.J. Stroud will lead Ohio State against Oregon.
C.J. Stroud will lead Ohio State against Oregon. / Kyle Robertson/Columbus Dispatch via
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The official opening week of the college football season was not short on drama.

The Georgia Bulldogs pulled off a notable upset against the Clemson Tigers, soaring up the odds to win the national championship this season at WynnBET. 

Alabama took care of business to remain the favorite, but with only a few AP Top 25 teams facing off in Week 2, there’s a good chance that the odds don’t seem much movement if the top teams can take care of business. 

No. 4 Ohio State and No. 11 Oregon will face off in the biggest matchup of Week 2 after the Ducks narrowly escaped Fresno State with a 31-24 win on Saturday. No. 18 Iowa and No. 7 Iowa State will battle for supremacy in The Hawkeye State on Saturday afternoon.

Here’s this week’s slate of AP Top 25 college football matchups, with all odds courtesy of WynnBET Sportsbook:

College Football Week 2 Odds -- Friday Sept. 10

No. 17 Coastal Carolina (1-0) vs. Kansas (1-0)

Time: 7:30 p.m. EST

Channel: ESPN 2

Line: Coastal Carolina -27.0

O/U: 53.0

College Football Week 2 Odds -- Saturday Sept. 11

No. 3 Ohio State (1-0) vs. No. 12 Oregon (1-0)

Time: 12:00 p.m. EST

Channel: FOX

Line: Ohio State -14.0

O/U: 63.5

South Florida (0-1) vs. No. 13 Florida (1-0)

Time: 1:00 p.m. EST

Channel: ABC

Line: Florida -29.0

O/U: 56.5

No. 8 Notre Dame (1-0) vs. Toledo (1-0)

Time: 2:30 p.m. EST

Channel: Peacock

Line: ND -17.5

O/U: 53.5

No. 2 Georgia (1-0) vs. UAB (1-0)

Time: 3:30 p.m. EST

Channel: ESPN 2

Line: Georgia -26.5

O/U: 44.5

Colorado (1-0) vs. No. 5 Texas A&M (1-0)

Time: 3:30 p.m. EST

Channel: FOX

Line: Texas A&M -17.0

O/U: 52.0

No. 7 Cincinnati (1-0) vs. Murray State (1-0)

Time: 3:30 p.m. EST

Channel: ESPN+

Line: N/A

O/U: N/A

No. 11 Penn State (1-0) vs. Ball State (1-0)

Time: 3:30 p.m. EST

Channel: FS1

Line: Penn State -22.5

O/U: 54.0

No. 1 Alabama (1-0) vs. Mercer (1-0)

Time: 4:00 p.m. EST

Channel: SEC Network

Line: N/A

O/U: N/A

No. 9 Iowa State (1-0) vs. No. 10 Iowa (1-0)

Time: 4:30 p.m. EST

Channel: ABC

Line: Iowa State -3.5

O/U: 45.0

No. 6 Clemson (0-1) vs. South Carolina State (0-1)

Time: 5:00 p.m. EST

Channel: ACC Network

Line: N/A

O/U: N/A

No. 4 Oklahoma (1-0) vs. Western Carolina (0-1)

Time: 7:00 p.m. EST

Channel: N/A

Line: N/A

O/U: N/A

No. 18 Wisconsin (0-1) vs. Eastern Michigan (1-0)

Time: 7:00 p.m. EST

Channel: FS1

Line: Wisconsin -25.0

O/U: 51.0

No. 22 Miami (0-1) vs. Appalachian State (1-0)

Time: 7:00 p.m. EST

Channel: ESPNU

Line: Miami -7.5

O/U: 54.5

Arkansas (1-0) vs. No. 15 Texas (1-0)

Time: 7:00 p.m. EST

Channel: ESPN

Line: Texas -6.0

O/U: 57.0

Louisiana (0-1) vs. Nicholls (0-1)

Time: 7:00 p.m. EST

Channel: ESPN 3

Line: N/A

O/U: N/A

No. 24 North Carolina (0-1) vs. Georgia State (0-1)

Time: 7:30 p.m. EST

Channel: ESPN 3

Line: UNC -25.5

O/U: 61.0

No. 17 Indiana (0-1) vs. Idaho (1-0)

Time: 7:30 p.m. EST

Channel: Big Ten Network

Line: N/A

O/U: N/A

LSU (0-1) vs. McNeese State (0-1)

Time: 8:00 p.m. EST

Channel: ESPN+, SEC Network

Line: N/A

O/U: N/A

No. 14 USC (0-1) vs. Stanford (0-1)

Time: 10:30 p.m. EST

Channel: FOX

Line: USC -17.5

O/U: 51.0

No. 23 Arizona State (1-0) vs. UNLV (0-1)

Time: 10:30 p.m. EST

Channel: ESPN 2

Line: ASU -33.0

O/U: 55.0


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